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Your Position: Home > Protein > Plasma Kallikrein/KLKB1 > KL1-M52H9

Mouse Plasma Kallikrein / KLKB1 Protein, His Tag

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This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    Fletcher factor,kallikrein B, plasma (Fletcher factor) 1,kininogenin,KLK3plasma kallikrein,KLKB1,plasma kallikrein heavy chain,plasma kallikrein light chain,Plasma Kallikrein,Plasma Prekallikrein,PPK,KLKB1
  • Source
    Mouse Plasma Kallikrein/KLKB1, His Tag(KL1-M52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Ala 638 (Accession # P26262-1 ).
    Predicted N-terminus: Gly 20
  • Molecular Characterization
    Plasma Kallikrein/KLKB1 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 71.1 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • Background
    Human Plasma Kallikrein, a serine protease, is synthesized in the liver and circulates in the plasma by binding to high molecular weight (HMW) kininogen or as a free zymogen. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Drug Development Status

  • Number of Launched Drugs:3 Details
  • Number of Drugs in Clinical Trials:7 Details
  • Latest Research Phase:Approved

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