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Your Position: Home > FcR > FcRn (FCGRT & B2M) > FCM-C52W8

Canine FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Tag Free

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  • Synonym
    FcRn,FCGRT & B2M
  • Source
    Canine FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (FCM-C52W8) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Ser 298 (FCGRT) & Val 28 - Asn 125 (B2M) (Accession # XP_038512242.1(FCGRT) & NP_001271408.1(B2M)).
    Predicted N-terminus: Ala 23
  • Molecular Characterization
    Online-Res(Ala 23 - Ser 298 (FCGRT) & Val 28 - Asn 125 (B2M)) XP_038512242.1 (FCGRT) & NP_001271408.1 (B2M)

    This protein .

    The protein has a calculated MW of 32.3 kDa (FCGRT) & 11.6 kDa (B2M).

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

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