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Your Position: Home > Non SARS-Cov-2 Kits > IL-1 beta > CEA-C002

ClinMax™Human Interleukin 1 beta (IL-1 beta) Quantitative ELISA Kit

For research use only.
  • Background
    ClinMax™Human IL-1β Quantitative ELISA Kit is designed to quantitate human IL-1β that is present in complex biological matrices, such as human serum, plasma, buffered solution, or cell culture. Interleukin-1β (IL-1β) is a potent pro-inflammatory cytokine. IL-1β is produced and secreted by various cell types, such as immune cells, fibroblasts, or cancer cells. The IL-1β gene is induced after "priming" of the cells and a second signal is required to allow IL-1β maturation by inflammasome-activated caspase-1. IL-1β is then released and leads to transcription of target genes through its ligation with IL-1R1 on target cells. IL-1β expression and maturation are guided by gene polymorphisms and by the cellular context. In cancer, IL-1β has pleiotropic effects on immune cells, angiogenesis, cancer cell proliferation, migration, and metastasis.
  • Application
    This immunoassay is designed to quantitate human IL-1β that is present in human serum, plasma, buffered solution, or cell culture. It has been calibrated against a highly purified human IL-1β and is evaluated with standard from NIBSC/WHO. Reference Reagent Interleukin-1β (Human, rDNA derived) NIBSC code: 86/680.
    It is for research use only.
  • Storage

    The unopened kit is stable for 12 months from the date of manufacture if stored at 2°C to 8°C. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.

  • Assay Principles

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Price(USD) : $590.00

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  • Number of Launched Drugs:5 Details
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  • Latest Research Phase:Approved

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