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Your Position: Home > Cytokines > CXCL13 > CX3-H1249

Human CXCL13 / BCA-1 Protein, His Tag

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  • Synonym
    C-X-C motif chemokine 13,Angie,B cell-attracting chemokine 1,BCA-1,B lymphocyte chemoattractant,CXC chemokine BLC,Small-inducible cytokine B13,CXCL13,BCA1,BLC,SCYB13
  • Source
    Human CXCL13 / BCA-1 Protein, His Tag(CX3-H1249) is expressed from E.coli cells. It contains AA Val 23 - Pro 109 (Accession # O43927-1 ).
    Predicted N-terminus: His
  • Molecular Characterization
    CXCL13 Structure

    This protein carries a polyhistidine tag at the N-terminus

    The protein has a calculated MW of 12.2 kDa.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    CXCL13, originally known as BLC (B-lymphocyte chemoattractant) or BCA-1 (B cell-attracting chemokine 1), is a homeostatic chemokine. It is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyers patches. CXCL13 plays a key role in orchestrating cell migration within spatially distinct regions of the secondary lymphoid organs. It strongly attracts B lymphocytes while promoting migration of only small numbers of T cells and macrophages. CXCL13 exerts its functions through its receptor CXCR5, which initially, was isolated from Burkitt Lymphoma and therefore designated as Burkitts lymphoma receptor 1 (BLR1).
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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