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Your Position: Home > TME Relevant Pathway > Laminin 121 E8 > LA1-H5261

Human Laminin 121 E8 Protein, Fc Tag

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    Laminin 121 E8,LN-121-E8,Laminin-121 E8
  • Source
    Human Laminin 121 E8, Fc Tag(LA1-H5261) is expressed from human 293 cells (HEK293). It contains AA Phe 1878 - Gln 2700 (Laminin alpha1E8) & Leu 1573 - Gln 1798 (Laminin beta2E8) & Asp 1528 – Pro 1609 (Laminin gamma1E8) (Accession # P25391-1 (Laminin alpha1E8) & P55268-1 (Laminin beta2E8) & P11047-1 (Laminin gamma1E8)).
    Predicted N-terminus: Phe 1878 (Laminin alpha1E8) & Pro(Laminin beta2E8) & Pro (Laminin gamma1E8)
  • Molecular Characterization

    This protein carries a human IgG1 Fc tag at the N-terminus

    The protein has a calculated MW of 92.2 kDa | 51.3 kDa | 35.6 kDa.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Laminin-121 is one of the α1 chain containing laminins. The α1 chain is detected at the 2-cell stage of the pre-implantation mouse embryo and is subsequently expressed mainly in many epithelial tissues during organogenesis. Laminin-121 showed the highest affinity to α6β1 and α7β1 integrins and furthermore, laminin-121 most effectively supported neurite outgrowth.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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