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Your Position: Home > Aneuro > Midkine > MIE-M5246

Mouse Midkine / Mdk Protein, His Tag

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    MDK,MEK,Midkine,MK1,MKARAP,NEGF2,Retinoic acid-induced differentiation factor
  • Source
    Mouse Midkine, His Tag(MIE-M5246) is expressed from human 293 cells (HEK293). It contains AA Lys 23 - Asp140 (Accession # P12025 ).
    Predicted N-terminus: His
  • Molecular Characterization
    Midkine Structure

    This protein carries a polyhistidine tag at the N-terminus

    The protein has a calculated MW of 15.0 kDa.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Midkine (MK or MDK), also known as neurite growth-promoting factor 2 (NEGF2), is a protein that in humans is encoded by the MDK gene. Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin (NEGF1, 46% homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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