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Your Position: Home > Receptor > KREMEN2 > KR2-R52H3

Rat Kremen-2 protein, His Tag

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    KREMEN2, Kremen-2, KRM2, Dickkopf receptor 2,Kringle domain-containing transmembrane protein 2
  • Source
    Rat Kremen-2, His Tag(KR2-R52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Arg 373 (Accession # D4ADS5 ).
    Predicted N-terminus: Gly 25
  • Molecular Characterization
    KREMEN2 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 39.2 kDa.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $400.00

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