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Your Position: Home > Inhibitor screening kits > CD47 > EP-152

CD47 [Biotinylated] : SIRP alphaV2 Inhibitor Screening ELISA Kit

For research use only.
This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Background
    CD47 is a transmembrane protein, a cell surface glycoprotein molecule belonging to the immunoglobulin superfamily that binds to a variety of proteins, including integrins, thrombospondin 1, and signal regulatory protein-α (SIRPα). In recent years, accumulating data have demonstrated that the CD47-SIRPαV2 axis is a key immune checkpoint in different cancers, including hematological malignancies, similar to PD-1/PD-L1 in solid tumors. CD47-SIRPαV2 blockade has become a next-generation immune checkpoint blocking strategy for various malignancies after PD-1/PD-L1.
  • Application

    This kit is developed for screening for inhibitors of human CD47 binding to human SIRP alphaV2.

    It is for research use only.

  • Storage
    The unopened kit is stable for 12 months from the date of manufacture if stored at 2°C to 8°C.

    The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.

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    Price(USD) : $650.00

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    Drug Development Status

    • Number of Launched Drugs:0 Details
    • Number of Drugs in Clinical Trials:36 Details
    • Latest Research Phase:Phase 3 Clinical

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