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Your Position: Home > Protein > CDNF > CDF-H5197

Human CDNF Protein, SUMO,His Tag

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    CDNF;Cerebral dopamine neurotrophic factorarginine-rich;mutated in early stage tumors-like 1; ARMETL1; ARMET-like protein 1; Conserved dopamine neurotrophic factor
  • Source
    Human CDNF Protein, SUMO,His Tag(CDF-H5197) is expressed from E.coli cells. It contains AA Gln 25 - Leu 187 (Accession # Q49AH0 ).
    Predicted N-terminus: Met
  • Molecular Characterization
    CDNF Structure

    This protein carries a SUMO tag at the N-terminus, followed by a polyhistidine tag

    The protein has a calculated MW of 18.5 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    CDNF is a member of the ARMET family and acts as a trophic factor for neurons. CDNF inhibits the (6-OHDA)-induced degeneration of neurons. When CDNF controlled after 6-OHDA-lesioning, it reestablishes the function and inhibits the degeneration of neurons in substantia nigra. CDNF is universally expressed in neuronal and non-neuronal tissues. The highest levels in the brain are found in the optic nerve and corpus callosum.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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