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Your Position: Home > Protein > CDNF > CDF-H5197

Human CDNF Protein, SUMO,His Tag

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  • Synonym
    CDNF;Cerebral dopamine neurotrophic factorarginine-rich;mutated in early stage tumors-like 1; ARMETL1; ARMET-like protein 1; Conserved dopamine neurotrophic factor
  • Source
    Human CDNF Protein, SUMO,His Tag(CDF-H5197) is expressed from E.coli cells. It contains AA Gln 25 - Leu 187 (Accession # Q49AH0 ).
    Predicted N-terminus: Met
  • Molecular Characterization
    CDNF Structure

    This protein carries a SUMO tag at the N-terminus, followed by a polyhistidine tag

    The protein has a calculated MW of 18.5 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    CDNF is a member of the ARMET family and acts as a trophic factor for neurons. CDNF inhibits the (6-OHDA)-induced degeneration of neurons. When CDNF controlled after 6-OHDA-lesioning, it reestablishes the function and inhibits the degeneration of neurons in substantia nigra. CDNF is universally expressed in neuronal and non-neuronal tissues. The highest levels in the brain are found in the optic nerve and corpus callosum.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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