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Your Position: Home > TME Relevant Pathway > Integrin alpha 10 beta 1 > IT1-R53W3

Rat Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein, His Tag&Tag Free

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    Integrin alpha 10 beta 1,ITGA10&ITGB1
  • Source
    Rat ITGA10&ITGB1 Heterodimer Protein, His Tag&Tag Free(IT1-R53W3) is expressed from CHO cells. It contains AA Phe 23 - Ser 1162 (ITGA10) & Gln 21 - Asp 729 (ITGB1) (Accession # D3ZW82-1 (ITGA10) & P49134-1 (ITGB1)).
    Predicted N-terminus: Phe 23 (ITGA10) & Gln 21 (ITGB1)
  • Molecular Characterization
    Integrin alpha 10 beta 1 Structure

    The protein has a calculated MW of 131.2 kDa | 83.7 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types I-VI and laminin-1 in a Mg(2+)-dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagen-binding I domain integrin, in addition to α1β1, α2β1 and α11β1. GROGER found in the N-terminal domain of collagens I and III, is only weakly recognised by α10β1, an important collagen receptor on chondrocytes, contrasting with the other collagen-binding integrins.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $410.00

Price(USD) : $2880.00

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