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Your Position: Home > Protein > Xanthine dehydrogenase > XDE-H5143

Human Xanthine dehydrogenase Protein, His Tag

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  • Synonym
    XAN1, XO, XOR
  • Source
    Human Xanthine dehydrogenase Protein, His Tag(XDE-H5143) is expressed from E. coli cells. It contains AA Thr 2 - Val 1333 (Accession # P47989-1 ).
    Predicted N-terminus: His
  • Molecular Characterization
    Xanthine dehydrogenase Structure

    This protein carries a polyhistidine tag at the N-terminus

    The protein has a calculated MW of 148.2 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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