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Your Position: Home > Protein > Cystatin SA > CS2-H5224

Human Cystatin SA / CST2 Protein, His Tag

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  • Synonym
    CST2,Cystatin-2,Cystatin-SA,Cystatin-S5
  • Source
    Human Cystatin SA, His Tag(CS2-H5224) is expressed from human 293 cells (HEK293). It contains AA Trp 21 - Ala 141 (Accession # AAH62679).
    Predicted N-terminus: Trp 21
  • Molecular Characterization
    Cystatin SA Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 15.2 kDa. The protein migrates as 15-16 kDa under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Cystatin SA SDS-PAGE

Human Cystatin SA, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Cystatin-2 (CST2) is also known as Cystatin-SA, Cystatin-S5, is a secreted thiol protease inhibitor, which belongs to the cystatin family. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The CST1, CST2, CST4, and CST5 are expressed in differential, tissue-specific patterns. CST2 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level) and is also expressed in submandibular gland and parotid gland.
  • Clinical and Translational Updates

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