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Your Position: Home > Antibody > Eribulin > ERN-MY2012b

Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11)

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  • Source

    Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11) is a Rabbit monoclonal antibody recombinantly expressed from HEK293 cells.

  • Clone

    1M1G11

  • Species

    Rabbit

  • Isotype

    Rabbit IgG | Rabbit Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Chemical

  • Immunogen

    Eribulin.

  • Specificity

    Specifically recognizes Eurblin.

  • Application
    ApplicationRecommended Usage
    ELISA0.06-31 ng/mL
  • Purity

    >90% as determined by SDS-PAGE.

  • Purification

    Protein A purified/ Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Eribulin SDS-PAGE

Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-ELISA
 Eribulin ELISA

Immobilized Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11) (Cat. No. ERN-MY2012b) at 1 μg/mL (100 μL/well) can bind Farletuzumab Ecteribulin diluted with 100% Mouse Serum with a linear range of 0.02-1.25 μg/mL (QC tested).

 Eribulin ELISA

Immobilized Farletuzumab Ecteribulin at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11) (Cat. No. ERN-MY2012b) with a linear range of 0.06-2 ng/mL (Routinely tested).

  • Background
    Eribulin is a synthetic analogue of the macrocyclic polyether halichondrin B, which was originally isolated from the Asian sea sponge Halichondria okadai. Eribulin binds specifically to the β-tubulin subunit on the (+) end of the microtubule and potently inhibits elongation of the formed microtubule, while having little or no effect on microtubule depolymerization. Eribulin's potent antimitotic activity and nonmitotic effects on tumor biology make it an interesting candidate for investigation as a MTA payload for ADCs.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $315.00

Price(USD) : $1890.00

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