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Human Mature PCSK9 (153-692) Protein, His Tag

  • Synonym
  • Source
    Human Mature PCSK9 (153-692), His Tag (PC9-H5226) is expressed from human 293 cells (HEK293). It contains AA Ser 153 - Gln 692 (Accession # Q8NBP7-1).
    Predicted N-terminus: Ser 153
  • Molecular Characterization
    Online(Ser 153 - Gln 692) Q8NBP7-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 58.1 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 10 mM HCl, pH2.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;

    2. -70°C for 3 months under sterile conditions after reconstitution.

Human Mature PCSK9 (153-692), His Tag (Cat. No. PC9-H5226) SDS-PAGE gel

Human Mature PCSK9 (153-692), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Human Mature PCSK9 (153-692), His TagHuman Mature PCSK9 (153-692), His Tag (Cat. No. PC9-H5226) ELISA bioactivity

Immobilized Human LDL R, Fc Tag (Cat. No. LDR-H5254) at 10 μg/mL (100 μL/well) can bind Human Mature PCSK9 (153-692), His Tag (Cat. No. PC9-H5226) with a linear range of 0.01-0.313 μg/mL (QC tested).

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Drug Development Status

  • Number of Launched Drugs:2 Details
  • Number of Drugs in Clinical Trials:24 Details
  • Latest Research Phase:Approved

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