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Your Position: Home > Antibody > p-tau181 > PT1-MY2073

Monoclonal Anti-Human p-tau181 Antibody, Mouse IgG2a (8D8C10) (MALS verified)

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  • Source

    Monoclonal Anti-Human p-tau181 Antibody, Mouse IgG2a (8D8C10) is a Mouse monoclonal antibody recombinantly expressed from HEK293 cells.

  • Clone

    8D8C10

  • Species

    Mouse

  • Isotype

    Mouse IgG2a | Mouse Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Human

  • Immunogen

    Recombinant polypeptide protein.

  • Specificity

    Specifically recognizes Human p-tau181 Protein.

  • Application
    ApplicationRecommended Usage
    ELISA0.3-313 ng/mL
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
p-tau181 SDS-PAGE

Monoclonal Anti-Human p-tau181 Antibody, Mouse IgG2a (8D8C10) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
p-tau181 MALS images

The purity of Monoclonal Anti-Human p-tau181 Antibody, Mouse IgG2a (8D8C10) (Cat. No. PT1-MY2073) is more than 90% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

Bioactivity-ELISA
 p-tau181 ELISA

Immobilized Recombinant Human P-Tau181, His tag at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human p-tau181 Antibody, Mouse IgG2a (8D8C10) (Cat. No. PT1-MY2073) with a linear range of 0.3-5 ng/mL (QC tested).

  • Background
    Tau, the microtubule‐associated protein, forms insoluble filaments that accumulate as neurofibrillary tangles in Alzheimer's disease (AD) and related tauopathies. Under physiological conditions, tau regulates the assembly and maintenance of the structural stability of microtubules. In the diseased brain, however, tau becomes abnormally hyperphosphorylated, which ultimately causes the microtubules to disassemble, and the free tau molecules aggregate into paired helical filaments.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $300.00

Price(USD) : $1980.00

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