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Your Position: Home > Bio-Markers & CD Antigens > Kallikrein 22 > Mouse Klk1b22 /KLK22 Protein

Mouse Kallikrein 22 / Klk1b22 Protein

  • Synonym
    Klk1b22,Klk22,EGF-BP A,kallikrein 22
  • Source
    Mouse Kallikrein 22, His Tag (KL2-M5224) is expressed from human 293 cells (HEK293). It contains AA Ala 18 - Pro 259 (Accession # NP_034244).
    Predicted N-terminus: Ala 18
  • Molecular Characterization
    Kallikrein 22(Ala 18 - Pro 259) NP_034244

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 27.3 kDa. The protein migrates as 32-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with 0.05% CHAPS. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss is observed after storage at:

    1. 4-8°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Mouse Kallikrein 22, His Tag (Cat. No. KL2-M5224) SDS-PAGE gel

Mouse Kallikrein 22, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Kallikrein 1-related peptidase b22 (Klk1b22) is also known as Beta-NGF-endopeptidase, Epidermal growth factor-binding protein type A (EGF-BP A), Glandular kallikrein K22 (mGK-22), Nerve growth factor beta chain endopeptidase, Tissue kallikrein 22 (KLK22), which belongs to the peptidase S1 family and Kallikrein subfamily. Klk1b22 contains one peptidase S1 domain. Klk1b22 preferential cleavage of Arg-|-Xaa bonds in small molecule substrates and highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $450.00

Price(USD) : $2980.00

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