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Your Position: Home > Antibody > AAV9 > AA9-Y2142

Monoclonal Anti-Adenoviruses AAV9 Antibody, Mouse IgG1 (28B9C5)

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  • Source

    Monoclonal Anti-Adenoviruses AAV9 Antibody, Mouse IgG1 (28B9C5) is a Mouse monoclonal antibody produced from a hybridoma created by fusing SP2/0 myeloma and Mouse B-lymphocytes.

  • Clone

    28B9C5

  • Species

    Mouse

  • Isotype

    Mouse IgG1 | Mouse Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Hybridoma Monoclonal

  • Immunogen

    AAV9

  • Specificity

    Specifically recognizes AAV9.

  • Application
    ApplicationRecommended Usage
    ELISA0.2-500 ng/mL
  • Purity

    >95% as determined by SDS-PAGE.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
SDS-PAGE
AAV9 SDS-PAGE

Monoclonal Anti-Adenoviruses AAV9 Antibody, Mouse IgG1 (28B9C5) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-ELISA
 AAV9 ELISA

Immobilized AAV9 at 1E+10capsids/ml (100 μl/well) can bind Monoclonal Anti-Adenoviruses AAV9 Antibody, Mouse IgG1 (28B9C5) (Cat. No. AA9-Y2142) with a linear range of 0.50-30ng/mL (QC tested).

  • Background
    AAV9 (Adeno-Associated Virus Serotype 9) is a highly efficient and safe gene therapy vector belonging to the Parvoviridae family. It is characterized by broad tissue tropism, enabling efficient transduction of the heart, liver, skeletal muscle, central nervous system (with the ability to cross the blood-brain barrier), and retina, among others. Compared to other serotypes, AAV9 exhibits stronger systemic diffusion capacity and lower immunogenicity, reducing the risk of host immune rejection. Its single-stranded DNA genome (~4.7 kb) allows long-term stable expression of transgenes but has a limited packaging capacity (≤5 kb).
    AAV9 has been utilized in clinical trials for various diseases, such as spinal muscular atrophy (SMA), Duchenne muscular dystrophy (DMD), and familial hypercholesterolemia.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $400.00

Price(USD) : $2770.00

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