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Your Position: Home > Antibody > CD69 > FABm022-01

PE-Labeled Monoclonal Anti-Human CD69 Antibody, Mouse IgG1 (3C5B7) (0.03% Proclin)

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  • Source
    PE-Labeled Monoclonal Anti-Human CD69 Antibody, Mouse IgG1 (3C5B7) is a mouse monoclonal antibody recombinantly expressed from Hybridoma.
  • Application
    Flow Cytometry (Evaluation of the expression of CD69 on Human cells).
  • Clone
    3C5B7
  • Species
    Mouse
  • Isotype
    Mouse IgG1 | Mouse Kappa
  • Specificity
    This product is a specific antibody specifically reacts with CD69 protein.
  • Reactivity

    Human

  • Immunogen

    Purified Human CD69 Protein.

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Isotype Control

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM1 for product information.

  • Recommended Dilution
    1:20
  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.2% BSA, 0.03% Proclin300 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
Bioactivity-FACS
 CD69 FACS

Flow cytometric analysis of Jurkat staining with PE-Labeled Monoclonal Anti-Human CD69 Antibody, Mouse IgG1 (3C5B7) (Cat. No. FABm022-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

  • Background
    The activation of T lymphocytes involves a wide variety of cellular changes. Some of these changes are biochemical in nature, such as phosphatidylinositol catabolism and the elevationof cellular calcium. Others are genetic, involving the induction of specific gene expression. Among the constellation of genes induced following T cell activation are several cell surface molecules. One of the earliest of these to be expressed is CD69 (previously known as activation inducer molecule or AIM, EA-1, Leu-23,and MLR3). Within one to two h of activation, CD69 can be found on the cell surface, with expression persisting at least three days. Studies with monoclonal antibodies (MAb) to CD69 have shown that it is a costimulatory molecule for T cell proliferation. In addition, CD69 expression can be induced on most, if not all, cells of hematopoietic origin.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $200.00

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Drug Development Status

  • Number of Launched Drugs:5 Details
  • Number of Drugs in Clinical Trials:9 Details
  • Latest Research Phase:Approved

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