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Your Position: Home > Protein > CD3E & CD3G > CDG-HA2W3

APC-Labeled CD3 epsilon&CD3 gamma Heterodimer Protein, Fc,His Tag&Fc,Flag Tag

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  • Synonym
    CD3 epsilon & CD3 gamma,CD3E & CD3G
  • Source
    APC-Labeled CD3E & CD3G Heterodimer Protein, Fc,His Tag&Fc,Flag Tag(CDG-HA2W3) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 & Gln 23 - Ser 116 (Accession # P07766-1 & P09693-1).
    Predicted N-terminus: Asp 23 & Gln 23
  • Molecular Characterization
    CD3E & CD3G Structure

    APC-Labeled CD3E & CD3G Heterodimer Protein, Fc,His Tag&Fc,Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 39.2 kDa (CD3E) and 38.6 kDa (CD3G). The subunit CD3E carries a human IgG1 Fc fragment at the C-terminus, followed by a polyhistidine tag. The subunit CD3G carries a human IgG1 Fc fragment at the C-terminus, followed by a flag tag.

  • Conjugate

    APC

    Excitation Wavelength: 640 nm

    Emission Wavelength: 661 nm

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
Bioactivity-ELISA
 CD3E & CD3G ELISA

Immobilized APC-Labeled CD3E & CD3G Heterodimer Protein, Fc,His Tag&Fc,Flag Tag (Cat. No. CDG-HA2W3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG1 (UCHT1) (Cat. No. CDE-M532) with a linear range of 0.1-4 ng/mL (QC tested).

  • Background
    T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
  • Clinical and Translational Updates

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Price(USD) : $450.00

Price(USD) : $2803.00

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Drug Development Status

  • Number of Launched Drugs:4 Details
  • Number of Drugs in Clinical Trials:6 Details
  • Latest Research Phase:Approved

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