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Your Position: Home > Protein > FCMR > FCR-H5253

Human FCMR Protein, Fc Tag

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  • Synonym
    FAIM3, FcmuR, TOSO
  • Source
    Human FCMR Protein, Fc Tag(FCR-H5253) is expressed from human 293 cells (HEK293). It contains AA Arg 18 - Gly 251 (Accession # O60667-1).
    Predicted N-terminus: Arg 18
  • Molecular Characterization
    FCMR Structure

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 52.4 kDa. The protein migrates as 65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method / rFC method.
  • Purity

    >80% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
FCMR SDS-PAGE

Human FCMR Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 80% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-ELISA
 FCMR ELISA

Immobilized Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgM (AM122) (Cat. No. SPD-M162) at 5 μg/mL (100 μL/well) can bind Human FCMR Protein, Fc Tag (Cat. No. FCR-H5253) with a linear range of 2-78 ng/mL (QC tested).

  • Background
    Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]
  • Clinical and Translational Updates

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