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Your Position: Home > Antibody > CD5 > FABm032-01

PE-Labeled Monoclonal Anti-Human CD5 Antibody, Mouse IgG1 (2C8A7) (0.03% Proclin)

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  • Source
    Monoclonal Anti-Human CD5 Antibody, Mouse IgG1 (2C8A7) is a mouse monoclonal antibody produced from hybridoma.
  • Application
    Flow Cytometry (Evaluation of the expression of CD4 on Human cells).
  • Clone
    2C8A7
  • Species
    Mouse
  • Isotype
    Mouse IgG1 | Mouse kappa
  • Specificity
    This product is a specific antibody specifically reacts with CD5 protein.
  • Reactivity

    Human

  • Immunogen

    Purified Human CD5 Protein

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Isotype Control

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM1 for product information.

  • Recommended Dilution
    1:20
  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.03% Proclin300, 0.2% BSA with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
Bioactivity-FACS
 CD5 FACS

Flow cytometric analysis of Jurkat staining with Anti-Human CD5 Antibody, Mouse IgG1 (2C8A7) (Cat. No. FABm032-01) FACS Protocol at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

  • Background
    T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $200.00

Price(USD) : $720.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:8 Details
  • Latest Research Phase:Phase 2 Clinical

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