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Polyclonal GFAP Antibody, Rabbit IgG

COADS MS
DS

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Cat. No. / Size
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GFP-S453-20ul
$80.00
GFP-S453-100ul
$415.00
ETA of in-stock products:2 business days
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Product Details

  • Source

    Polyclonal GFAP Antibody, Rabbit IgG is a polyclonal antibody purified from rabbit serum.
    Gene Synonyms: glial fibrillary acidic protein.

  • Species

    Rabbit

  • Isotype

    Rabbit IgG

  • Antibody Type

    Polyclonal Antibody

  • Immunogen

    Mouse GFAP fragment fused to GST

  • Specificity

    This product is a specific antibody specifically reacts with GFAP.

  • Application

    Application
    Recommended Usage
    IF
    1:200~500

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Supplied as 0.2 μm filtered solution in pH7.4, PBS, 50 mM Tris, 50 Mm Glycine with 40% glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Shipped at -20°C. Store at -20°C for 20 months;
    2. Shipped at -20°C. Store at -70°C for 3 years.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Immunostaining

    GFAP IMMUNOSTAINING

    2D cell staining: Immunofluorescent staining (10X) of cerebral organoid-derived neurons (CIPO-BWL001K) labeling GFAP (Red) with purified GFP-S453 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.

  • GFAP IMMUNOSTAINING

    3D organoid staining: Immunofluorescent staining (10X) of cerebral organoid (CIPO-BWL001K) labeling GFAP (Green) with purified GFP-S453 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.

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Background

The glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature astrocytes, but also an important component of the cytoskeleton in astrocytes during development. GFAP has been shown to be involved in astrocyte functions, which are important during regeneration, synaptic plasticity and reactive gliosis. It is used as a marker to distinguish astrocytes from other glial cells during development.

Middeldorp J, Hol EM. Prog Neurobiol. 2011;93(3):421-43. doi: 10.1016/j.pneurobio.2011.01.005.

General Notes: FOR RESEARCH USE ONLY.

Recent Advances

 
Drug Development Progress
  • English Name：

    Glial fibrillary acidic protein

  • Category：

  • Approved Drugs：

    1 Details

  • Drugs in Clinical Trials：

    1 Details

  • Highest Development Stage：

    Approved

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