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Your Position: Home > Protein > S100P > S1P-H5110

Human S100P / S100E Protein, Tag Free

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  • Synonym
    S100P,S100E,MIG9
  • Source
    Human S100P, Tag Free(S1P-H5110) is expressed from E. coli cells. It contains AA Met 1 - Lys 95 (Accession # AAH06819 ).
    Predicted N-terminus: Met
  • Molecular Characterization
    S100P Structure

    This protein carries no "tag"

    The protein has a calculated MW of 10.4 kDa. The protein migrates as 10.4 kDa under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
S100P SDS-PAGE

Human S100P, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    S100 calcium-binding protein P (S100P),a member of the S-100 family, is also known as protein S100-P, migration-inducing gene 9 protein (MIG9) and protein S100-E,which contains two EF-hand domains. As for subunit structure,S100P is homodimer and heterodimer with S100A1. S100P may function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, S100P functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. Furthermore,S100P may stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
  • Clinical and Translational Updates

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