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Recombinant Proteins & Antibodies

  • Antibody-Drug Conjugates (ADCs): the Magic Bullets for Treatment
  • Emerging mutants from SARS-CoV-2 Variants
  • IgG Fc Proteins——Ideal Isotype Control for IgG Structured Drug Development
Insights

Advances in PSMA-targeted therapy for prostate cancer

Decrease or increase, two therapeutic strategies via FcRn-mediated mechanism

【Inspiring Target】Therapeutic potential of IL-6 immunization in multiple fields continues to burst

Omicron Antigens and Antibodies at Gram-level Supply: Backing Up Diagnostic Reagents Development

SARS-CoV-2 Mutants

Emerging VoCs, Lambda, Delta, Beta, Alpha mutants and so on, including RBD, S trimer, S1, NTD, NP, etc. These mutants are of high purity and bioactivity and can be used to evaluate the efficacy of the antibodies and vaccination.

SARS-CoV-2 Related Kits

ELISA kits for neutralizing antibody titer assay, binding antibody titer assay, antibody isotype assay, antigen titer assay and inhibitor screening, etc., which can accelerate the research and development of anti-SARS-CoV-2 drugs and vaccines.

Targets of CAR-T Cell Therapy

50+ targets designed for CAR detection, including PE/FITC/biotin labeled proteins. The key reagents for CD19 and BCMA were FDA DMF filed which can support your IND, NDA and BLA process.                  

Full-length Transmembrane Proteins

Full length multi-pass TPs with stabilized structure and high bioactivity for immunization, antibody screening, cell based assay and CAR detection, including hot CD20, Claudin 18.2， CD133, GPRC5D，CCR8, CCR5, etc.

Targets for ADCs

To meet the needs of ADCs development, ACROBiosystems can provide: A variety of high-quality target proteins; MMPs/Cathepsin/uPA for cleavable linker; Anti-payload antibodies & anti-idiotypic antibodies for immunogenicity and PK analysis; SPR/BLI analytical and ADA development service.

Immune Checkpoints

A series of immune checkpoints including classic co-inhibitory and co-stimulatory receptors. The comprehensive catalog contains 100+ targets with various species and tags, and the high-quality proteins are in good batch-to-batch consistency.

Cytokines

Comprehensive cytokines including IL families, growth factors, chemokines, TNFs, etc. These products are HEK293 expressed and nearly in authentic structure, high purity and bioactivity, cell based assay/SPR/BLI verified.

BsAb targets

CD3 proteins and a collection of for bispecific antibody development which are of high specificity and bioactivities and suitable for immunization, antibody screening.

Fc Receptors

Comprehensive collection of Fc receptor proteins, including their common variants, which can help expedite your antibody development.

MABSOL® Biotinylated Proteins

The MABSOL biotinylated protein collection includes more than a hundred commonly studied drug targets and biomarker proteins.

Enzymes

Series of target enzymes, including ATP related enzymes, protease, kinase, and tool enzymes, including Nuclease, IdeS, Endo S, etc.

Anti-idiotypic Antibodies

To support preclinical/clinical immunogenicity and PK analysis, ACROBiosystems has developed a series of high-affinity anti-idiotypic antibodies. Our pipeline covers five hot targets including adalimum*b, rituxim*b, cetuxim*b, trastuzum*b, and bevacizum*b.

Newly Added Products

Mutants from SARS-CoV-2 Emerging Variants Omicron and more

ACROBiosystems are going full steam ahead on developing a collection of recombinant antigens for emergency SARS-CoV-2 variants. The reagents can be used to evaluate the efficacy of the antibodies and vaccination.

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Star Staining fluorescent-labeled products

Star Staining products are developed by a new-generation site-specific labeling technology with Star Standard quality. These products are uniquely designed for detecting and monitoring CAR-T cells in clinical trials.

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News Center

Advances in PSMA-targeted therapy for prostate cancer
2022/01/27
Advances in PSMA-targeted therapy for prostate cancer
Prostate-specific membrane antigen (PSMA), a transmembrane glycoprotein located on the cell membrane, is specifically and highly expressed in prostate cancer (PCa). Besides, its expression level is related to tumor invasiveness. As a molecular target of PCa, PSMA has been extensively studied in the
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Decrease or increase, two therapeutic strategies via FcRn-mediated mechanism
2022/01/25
Decrease or increase, two therapeutic strategies via FcRn-mediated mechanism
On December 17, 2021, Argenx announced that the FDA has approved VYVGART™ (EFgartigimod AlFA-FCAB), the world's first antibody drug targeting FcRn. It is used to treat general Myasthenia gravis (gMG) in adults with positive anti-acetylcholine receptor (AChR) antibody. As early as January 2021, Zai L
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Congratulations to ACROBiosystems being Listed on domestic Shenzhen Stock Exchange
2021/10/21
Congratulations to ACROBiosystems being Listed on domestic Shenzhen Stock Exchange
ACROBiosystems is pleased to announce that on October 18, 2021 Beijing local time, the company was listed onthe Shenzhen Stock Exchange.
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PepTalk 2022
2022/01/17 - 2022/01/19
PepTalk 2022
Speaker: Nicholas J. Abuid, Ph.D, ACROBiosystems；Hanns-Christian Mahler, PhD, Paul Parren, PhD，And more
Time: January 17 - 19, 2022
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