Overcoming Challenges from Discovery to the Clinic with Innovative Tools and Solutions

CAR Target Proteins

Recombinant Protein Targets that are commonly used for CAR discovery and development.A variety of tags and fluorescent labels are available for you to discover!

● CD19
● BCMA
● Mesothelin

MHC-peptide complexes

Looking for recombinant MHC proteins? Our MHC proteins come in either monomeric or tetrameric forms and are expressed using our HEK293 platform to ensure the structure is as close to its native structure as possible!

● MHC skeleton (peptide-free)
● MHC monomers
● MHC tetramers

Aneuro: Proteins for Neuroscience

Neurological disorders such as Alzheimers are driven by mutagenic proteins that aggregate and cause neural cell death. Explore our recombinant proteins to assist your research into neuroscience and discover new drug targets to combat neurodegenerative diseases.

● Tau
● Alpha-Syn

ComboX: Streptavidin Series

The interaction between Streptavidin and biotin is one of the most commonly utilized interactions in biology for screening, purification, and assay development.

● SA-conjugated Magnetic Beads
● SA-conjugated 96 well plates
● SA recombinant proteins

IHC Antibodies

Immunohistochemistry is a standard for clinical diagnostics, helping identify the spatial distribution of cancer markers that can help clarify treatment strategies and available therapies.

● Claudin 18.2 IHC Antibodies
● PD-L1 IHC Kit

GMP & Premium Grades

High-quality life science tools and solutions designed for use in cell therapy manufacturing that are animal-origin free, sterile, ultra-low endotoxin, and with related regulatory support.

● GMP-grade Growth Factors
● Premium-grade Growth Factors
● Premium-grade Activation Beads

Cell Culturing

Growth factors and other tools to assist with culturing iPSCs, MSC, neural cells, organoids and much more!

● Cell Culture Cytokines and Antibodies
● Cell Activation Beads
● Xeno-free Cell Culture Matrix Proteins
● Aneuro: Neural Factors

Nucleic Acid Removal

Sample cleanup is a necessary part of manufacturing designed to prepare the final therapeutic for patient safety and successful IND application. Explore our nucleases designed to remove nucleic acid residues.

● GENIUS: Nuclease

Gene-editing

Viral vectors are a critical part of genetically modifying immune cells to express CAR receptors and maximize cell therapy efficacy.

● GENIUS Cas Enzymes
● mRNA Synthesis Enzymes

Custom GMP Services

Can’t find the reagents you are looking for in your studies? Contact us and fill out our inquiry form and we can directly synthesize the perfect GMP product for your needs.

● GMP-grade Growth Factors & Proteins
● GMP Cell-grade Beads

Large-Scale Manufacturing

Scale-up your current manufacturing with us! We can scale up our GMP-products in accordance to your needs starting from g to kg of GMP-grade products.

● GMP-grade Growth Factors

CAR Detection

Detection of CAR-Expression is critical in evaluating the efficacy of your CAR modification. Explore our products designed to help you evaluate CAR expression.

● Anti-FMC63 Antibodies
● Star Staining - Fluorescent Conjugated Proteins

Residual Detection

Manufacturing biologics is a complex process that can introduce a wide variety of residues that can compromise the safety of the final therapeutic. Use our kits to detect for residues and ensure that your therapy is ready for the clinical stage.

● Host DNA / Protein Kits
● Residual enzyme ELISA Kits
● Pre-coupled Bead Detection Kits

Potency Assay

Potency assays are a critical part of evaluating therapeutic efficacy against the target it was developed for. Use our kits to quickly study your therapeutic potency.

● Cytokine release assay
● Multiplexed cytokine assays
● Stable cell lines

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models. For cell therapies, PK assays are desigend to evaluate the presence of CAR cells post-therapeutic delivery.

● Anti-FMC63 Antibodies
● Star Staining - Fluorescent Conjugated Proteins
● Anti-idiotypic Antibody Development

Pharmacodynamic Studies

Pharmacodynamics is complementary to pharmacokinetics, which observes the mechanism of action of each therapy. We offer a wide variety of cell-based models and other life science tools to accelerate your PD studies.

● Organoid Culture Cytokines
● Pre-formed Fibrils (Aneuro)
● Diagnostic Biochips

Immunogenicity Studies

Even CAR cells are immunogenic, despite its patient-derived origins. Evaluating the immunogenicity of any therapeutic is critical in ensuring safety.

● Anti-FMC63 antibody
● Immunogenicity Anti-FMC63 ELISA kit
● Star-staining - Fluorescent labeled Proteins

Toxicity Studies

A big side effect of CAR therapies is cytokine release syndrome. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

● Cytokine release assay
● Multiplexed cytokine assays

Pharmacokinetic Studies

● Anti-FMC63 Antibodies
● Star Staining - Fluorescent Conjugated Proteins
● Anti-idiotypic Antibody Development

Toxicity Studies

A big side effect of CAR therapies is cytokine release syndrome. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

● Cytokine release assay
● Multiplexed cytokine assays

Immunogenicity Studies

Even CAR cells are immunogenic, despite its patient-derived origins. Evaluating the immunogenicity of any therapeutic is critical in ensuring safety.

● Anti-FMC63 antibody
● Immunogenicity Anti-FMC63 ELISA kit
● Star-staining - Fluorescent labeled Proteins

GenPower
Gene-editing enzymes

Discovery & Development
CMC-Manufacturing
CMC-Quality Control
Preclinical Studies
Clinical Studies

Companion Diagnostics Development

Premium & GMP-grade Raw Materials

GenPower
Gene-editing enzymes

Custom GMP-grade Protein Services

Gene-editing

Viral vectors are a critical part of genetically modifying immune cells to express CAR receptors and maximize cell therapy efficacy.

● GENIUS Cas Enzymes
● mRNA Synthesis Enzymes

IHC Antibodies

Immunohistochemistry is a standard for clinical diagnostics, helping identify the spatial distribution of cancer markers that can help clarify treatment strategies and available therapies.

● Claudin 18.2 IHC Antibodies
● PD-L1 IHC Kit

GMP & Premium Grades

High-quality life science tools and solutions designed for use in cell therapy manufacturing that are animal-origin free, sterile, ultra-low endotoxin, and with related regulatory support.

● GMP-grade Growth Factors
● Premium-grade Growth Factors
● Premium-grade Activation Beads

Custom GMP Services

Can’t find the reagents you are looking for in your studies? Contact us and fill out our inquiry form and we can directly synthesize the perfect GMP product for your needs.

● GMP-grade Growth Factors & Proteins
● GMP Cell-grade Beads

Nucleic Acid Removal

● GENIUS: Nuclease

Gene-editing

Viral vectors are a critical part of genetically modifying immune cells to express CAR receptors and maximize cell therapy efficacy

● GENIUS Cas Enzymes
● mRNA Synthesis Enzymes

Large-Scale Manufacturing

Scale-up your current manufacturing with us! We can scale up our GMP-products in accordance to your needs starting from g to kg of GMP-grade products.

● GMP-grade Growth Factors

Residual Detection

● Host DNA / Protein Kits
● Residual enzyme ELISA Kits
● Pre-coupled Bead Detection Kits

Potency Assay

Potency assays are a critical part of evaluating therapeutic efficacy against the target it was developed for. Use our kits to quickly study your therapeutic potency.

● Cytokine release assay
● Multiplexed cytokine assays
● Stable cell lines

Pharmacodynamic Studies

● Organoid Culture Cytokines
● Pre-formed Fibrils (Aneuro)
● Diagnostic Biochips

Toxicity Studies

A big side effect of CAR therapies is cytokine release syndrome. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

● Cytokine release assay
● Multiplexed cytokine assays

Toxicity Studies

A big side effect of CAR therapies is cytokine release syndrome. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

● Cytokine release assay
● Multiplexed cytokine assays

FLAG
Transmembrane Proteins

Discovery & Development
CMC-Manufacturing
CMC-Quality Control
Preclinical Studies
Clinical Studies

Immune Checkpoint Proteins

Biotinylated Proteins

Fc Proteins

GMP GENIUS Nuclease

Enzymes for Antibody Characterization

ComboX
IgG Isotype Control

Therapeutic Antibody Targets

Therapeutic antibodies target a wide variety of tumor biomarkers to target and home onto specific cell types. We offer a wide array of target proteins to assist with the development of antibodies.

● Transmembrane Proteins
● Immune Checkpoints
● MHC Peptide Complexes

Fc Receptor Proteins

The efficacy of a therapeutic antibody depends on the Fc fragment and its interaction with key Fc receptors. Test your antibody against a panel of receptors during antibody engineering.

● Neonatal Fc receptors
● Fc proteins and Fc Receptors

Antibody Screening Tools

Screening antibody workflows can take on various forms with different reagents and instruments used. Explore our wide array of reagents to assit with developing your own screneing workflow.

● Biotinylated Proteins
● Inhibitor Screening Kits
● Pre-coupled Magnetic Beads

Stable Cell Lines (Cellinsight)

Cell lines are a critical part of evaluating and developing antibodies. Explore our cell line products or inquire about a custom cell line within.

● Stable Cell Lines

Nucleic Acid Removal

● GENIUS: Nuclease

Enzymes for Antibody Characterization

Undertstanding the conjugation and sequence of antibodies are critical for development success.

● Glycan removal
● Antibody cleavage

Residual Detection

● Host DNA / Protein Kits
● Residual enzyme ELISA Kits
● Pre-coupled Bead Detection Kits

Stable Cell Lines (Cellinsight)

Cell lines are a critical part of evaluating and developing antibodies. Explore our cell line products or inquire about a custom cell line within.

● Stable Cell Lines

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models.

● Biotinylated Proteins
● SA-coated Plates
● Anti-idiotypic Antibodies

Pharmacodynamic Studies

● Organoid Culture Cytokines
● Pre-formed Fibrils (Aneuro)
● Diagnostic Biochips

Immunogenicity Studies

Evaluating the immunogenicity of any therapeutic is critical in ensuring safety along with other toxicity studies.

● Anti-idiotypic Antibody Development Service

Toxicity Studies

Cytokine release syndrome is a major concern for all new therapeutics. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

● Cytokine release assay
● Multiplexed cytokine assays

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models.

● Biotinylated Proteins
● SA-coated Plates
● Anti-idiotypic Antibodies

Immunogenicity Studies

Evaluating the immunogenicity of any therapeutic is critical in ensuring safety along with other toxicity studies.

● Anti-idiotypic Antibody Development Service

Toxicity Studies

Cytokine release syndrome is a major concern for all new therapeutics. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

● Cytokine release assay
● Multiplexed cytokine assays

Discovery & Development
CMC-Manufacturing
CMC-Quality Control
Preclinical Studies
Clinical Studies

ADC Drug Targets

ADC Conjugation Kits

Fc Proteins

GMP GENIUS Nuclease

ADC Conjugation Kits

Enzymes for Antibody Characterization

Anti-payload Antibodies

ComboX
IgG Isotype Control

ADC Drug Targets

Antibody drug conjugates target a wide variety of tumor biomarkers to target and home onto specific cell types. We offer a wide array of target proteins to assist with the development of ADCs.

● ADC Target Proteins
● Tumor Microenvironment Proteins

ADC Conjugation Kits

Conjugating a payload onto antibodies can be challenging with the wide variety of methodologies and linkers. Use our kits to quickly conjugate your target payload onto antibodies in a site-specific methodology.

● MMAE (DAR2) ADC Conjugation Kit
● MMAE (DAR4) ADC Conjugation Kit

Fc Receptor Proteins

The efficacy of a therapeutic antibody depends on the Fc fragment and its interaction with key Fc receptors. Test your antibody against a panel of receptors during antibody engineering.

● Neonatal Fc receptors
● Fc proteins and Fc Receptors

Antibody Screening Tools

Screening antibody workflows can take on various forms with different reagents and instruments used. Explore our wide array of reagents to assit with developing your own screneing workflow.

● Biotinylated Proteins
● Inhibitor Screening Kits
● Pre-coupled Magnetic Beads

Proteases for Peptide Linkers

Enzymes designed to cleave peptide linkers are a critical component of delivering ADC payloads. Explore our array of proteases to assist with your ADC linker development.

● Coming Soon!

Stable Cell Lines (Cellinsight)

Cell lines are a critical part of evaluating and developing antibodies. Explore our cell line products or inquire about a custom cell line within.

● Stable Cell Lines

Nucleic Acid Removal

● GENIUS: Nuclease

ADC Conjugation Kits

● MMAE (DAR2) ADC Conjugation Kit
● MMAE (DAR4) ADC Conjugation Kit

Anti-payload Antibodies

Evaluate and quantify the amount of payload delivered on your antibodies or evaluate drug-to-antibody ratio to ensure a consistent therapeutic payload delivery.

● Anti-MMAE Antibody
● Anti-DXD Antibody

Enzymes for Antibody Characterization

The antibody part of ADCs are a major component that contribute to the therapeutic efficacy. Undertstanding the conjugation and sequence of antibodies are critical for development success.

● Glycan removal
● Antibody cleavage

Residual Detection

● Host DNA / Protein Kits
● Residual enzyme ELISA Kits
● Pre-coupled Bead Detection Kits

Stable Cell Lines (Cellinsight)

Cell lines are a critical part of evaluating and developing antibodies. Explore our cell line products or inquire about a custom cell line within.

● Stable Cell Lines

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models. For cell therapies, PK assays are desigend to evaluate payload delivery concentration.

● Anti-payload Antibodies
● Biotinylated Proteins
● SA-coated Plates
● Anti-idiotypic Antibodies

Pharmacodynamic Studies

● Organoid Culture Cytokines
● Pre-formed Fibrils (Aneuro)
● Diagnostic Biochips

Immunogenicity Studies

Evaluating the immunogenicity of any therapeutic is critical in ensuring safety along with other toxicity studies.

● Anti-idiotypic Antibody Development Service

Toxicity Studies

Cytokine release syndrome is a major concern for all new therapeutics. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

● Cytokine release assay
● Multiplexed cytokine assays

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models. For cell therapies, PK assays are desigend to evaluate payload delivery concentration.

● Anti-payload Antibodies
● Biotinylated Proteins
● SA-coated Plates
● Anti-idiotypic Antibodies

Immunogenicity Studies

Evaluating the immunogenicity of any therapeutic is critical in ensuring safety along with other toxicity studies.

● Anti-idiotypic Antibody Development Service

Toxicity Studies

Cytokine release syndrome is a major concern for all new therapeutics. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

● Cytokine release assay
● Multiplexed cytokine assays

ELISPOT Services
^{Coming Soon}

Discovery & Development
CMC-Manufacturing
CMC-Quality Control
Preclinical Studies
Clinical Studies

ViruStop
Viral Antigens

Pseudovirus Services

mRNA Synthesis Enzymes
^{Coming Soon}

Antigen Detection Kits
^{Coming Soon}

Antibody Pairs
^{Coming Soon}

Neutralizing Antibodies

Specific Antibodies
^{Coming Soon}

Antibody Titer Assay Kits

Neutralizing Antibodies

Antibody Titer Assay Kits

Pseudovirus Services

Neutralizing Antibodies

Virustop

Virus antigens play a critical role in viral infection. We offer a wide array of antigens for infectious diseases including:

● TSARS-CoV-2
● Monkeypox

Pseudovirus Services

Pseudoviruses are non-viral, virus antigen presenting particles that mimic viruses without infectiousness and safety concerns of using live viruses. The availability of pseudoviruses enables a wide range of experimental studies without compromising lab safety.

● Pseudoviruses
● Pseudovirus Services

Gene-editing

Modification of nucleic acids and other virus vectors are a critical part of vaccine development. Enzymes designed for synthesizing nucleic acids include:

● GENIUS Cas Enzymes
● mRNA Synthesis Enzymes

Antigen Detection

Evaluating the presence of antigen is required to ensure that vaccines are delivering the correct virus antigen to induce antibody production.

● RSV
● VZV
● SARS-CoV-2

Coming Soon >>

Antibodies

Antigen-specific antibodies are critical in quantifying the efficacy of vaccines by evaluating the antibody titer after immunization.

● Neutralizing Antibodies
● Specific Antibodies
● Antibody Pairs

Residual Detection

● Host DNA / Protein Kits
● Residual enzyme ELISA Kits
● Pre-coupled Bead Detection Kits

Antibody Titer Assay Kits

Quantifying antibody titer is the primary endpoint for vaccine development. Ensuring patients develop a sufficiently high antibody titer against certain antigens means patients are able to develop a protection against future infection or severe disease.

● SARS-CoV-2

Antibodies

Antigen-specific antibodies are critical in quantifying the efficacy of vaccines by evaluating the antibody titer after immunization.

● Neutralizing Antibodies
● Specific Antibodies
● Antibody Pairs

Toxicity Studies

Ensuring that vaccines delivered are not toxic is a priority to any therapy during the preclinical and clinical stages.

● Cytokine release assay
● Multiplexed cytokine assays