Overcoming Challenges from Discovery to the Clinic with Innovative Tools and Solutions

CAR Target Proteins

Recombinant Protein Targets that are commonly used for CAR discovery and development.A variety of tags and fluorescent labels are available for you to discover!

Universal CAR Detection Tool

The universal CAR detection tool is FACS validated for highly specific and sensitive binding to CAR cells with broad applicability. It provides comprehensive support throughout the development process of cell therapy drugs.

MHC-peptide complexes

Looking for recombinant MHC proteins? Our MHC proteins come in either monomeric or tetrameric forms and are expressed using our HEK293 platform to ensure the structure is as close to its native structure as possible!

Aneuro: Proteins for Neuroscience

Neurological disorders such as Alzheimers are driven by mutagenic proteins that aggregate and cause neural cell death. Explore our products to assist your research into neuroscience and discover new drug targets to combat neurodegenerative diseases.

ComboX: Streptavidin (SA) Series

The interaction between Streptavidin and biotin is one of the most commonly utilized interactions in biology for screening, purification, and assay development.

Early Pharmacodynamic Assessment

In the early stages of biopharmaceutical development, it is crucial to provide highly sensitive, specific, and validated immunoassay products for cytokines and biomarkers. These assays enable quantitative detection of target analytes across various species, facilitating the verification of drug mechanisms and efficacy evaluations.

Immunohistochemistry (IHC) Antibodies

Immunohistochemistry (IHC) is an antibody-based technique used for the localization, qualitative, and quantitative analysis of antigens within tissue cells. It is widely applied in medical research, biological detection, and pathological diagnosis.

GMP-grade Growth Factors

Strictly following the GMP quality system, we provide multiple GMP grade cytokines to support the large-scale manufacturing and differentiation of immune cells, stem cells, and other cell types.

Extracellular Matrix (ECM) Proteins

Specially designed to support the large-scale manufacturing needs of stem cells (iPSC/ESC/MSC, etc.), rigorously tested to ensure compliance with the highest standards, providing excellent performance for stem cell research and drug development.

Serum-free Cell Culture Medium

Provide culture media suitable for various types of cell cultures such as T cells, NK cells, CAR-T, CIK, CAR-NK, etc; Chemically defined, no serum, animal origin-free, higher expansion efficiency!

Cell Activation

A series of tools for cell activation, such as classical antibodies, magnetic beads, and specific antigen coupled magnetic beads, have been validated at the cellular level and can efficiently stimulate and expand target cells, better assisting the development process of cell therapy drugs.

Gene Editing

Gene editing technology is widely used in gene therapy and CAR cell therapy, typically using delivery systems such as viral vectors to deliver specific genetic material into specific target cells, modifying the expression of individual genes or repairing abnormal genes. We focus on the CGT field and provide high-quality gene editing related tools.

Residual Nucleic Acid Removal

Sample cleanup is a necessary part of manufacturing designed to prepare the final therapeutic for patient safety and successful IND application. Explore our nucleases designed to remove nucleic acid residues.

Solutions

Our various solutions aim to provide customers with a more comprehensive and high-quality service experience, and accelerate the commercialization of CGT drugs!

Custom GMP-grade Products

We have an experienced Custom GMP-grade Products team and a high standard GMP factory, which can provide you with strong support. It has advantages such as compliance with regulatory requirements, audit-friendly, high customization and flexible adaptation capabilities, and strong application development support.

GMP-Resilient Supply

The GMP-Resilient Supply aims to provide global customers with more flexible, resilient, low-risk, high-quality, and professionally supported solutions, accelerating the development and launch process of CGT biopharmaceuticals.

CAR Target Proteins

Star Staining fluorescent-labeled products are developed by a new-generation site-specific labeling technology with "Star Standard" quality at ACROBiosystems. These products are uniquely designed to fully meet diverse quality control needs for CAR-positive rate detection.

Anti-Linker Antibodies

We are dedicated to developing a series of anti-Linker antibodies, such as G4S Linker and Whitlow/218 Linker, covering various fluorescent labels including PE, APC, and Alexa Fluor™, providing groundbreaking solutions for CAR molecule characterization and functional testing. Additionally, we offer premium-grade anti-Linker antibodies and magnetic beads, ideal for key applications like cell activation and sorting.

Safety Testing Kits

Based on pharmacopeial standards and international regulations, we develop endotoxin, mycoplasma, and sterility test kits for biopharmaceutical quality control, providing comprehensive safety testing solutions.

CMC Residue Detection Kits

Manufacturing biologics is a complex process that can introduce a wide variety of residues that can compromise the safety of the final therapeutic. Use our kits to detect for residues and ensure that your therapy is ready for the clinical stage.

Flow Cytometry Analysis Platform

Leveraging our flow cytometry analysis platform, we are dedicated to providing precise drug characterization and activity analysis solutions to advance drug quality control and clinical evaluation.

mRNA-LNP Characterization

We provide high-quality fluorescent-labeled proteins for precise antibody density quantification on Ab-LNPs, supporting the development of in vivo CAR-T cell therapies.

ELISA Kits

The ClinMax™ ELISA Kit is a ready-to-use immunoassay kit, validated with biological samples. We offer quantitative kits for various targets, including cytokines and biomarkers, ensuring accurate, specific, and reliable results.

Functional Cell lines (Cellinsight)

Analysis and evaluation at the cellular level is one of the important indicators for evaluating drug effectiveness in vitro and is widely used in the process of new drug development.

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models. For cell therapies, PK assays are desigend to evaluate the presence of CAR cells post-therapeutic delivery.

Pharmacodynamic Studies

Pharmacodynamics is complementary to pharmacokinetics, which observes the mechanism of action of each therapy. We offer a wide variety of cell-based models and other life science tools to accelerate your PD studies.

Immunogenicity Studies

Even CAR cells are immunogenic, despite its patient-derived origins. Evaluating the immunogenicity of any therapeutic is critical in ensuring safety.

Toxicity Studies

A big side effect of CAR therapies is cytokine release syndrome. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

Immunohistochemistry (IHC) Antibodies

Pharmacokinetic Studies

Biomarker and Translational Research

In clinical research, biomarker analysis plays a pivotal role in exploratory studies, internal decision-making, and serving as clinical endpoints. We offer both traditional and novel biomarker detection kits to support clinical phase experiments. Our product range encompasses a variety of biomarkers to meet diverse research needs.

Toxicity Studies

A big side effect of CAR therapies is cytokine release syndrome. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

Immunogenicity Studies

Even CAR cells are immunogenic, despite its patient-derived origins. Evaluating the immunogenicity of any therapeutic is critical in ensuring safety.

Immunohistochemistry (IHC) Antibodies

GenPower
Gene-editing enzymes

Discovery & Development
CMC-Manufacturing
CMC-Quality Control
Preclinical Studies
Clinical Studies

AAV Titer Quantitation

Early Pharmacodynamic Assessment

GenPower
Gene-editing enzymes

AAV Titer Quantitation

Premium(Pre-GMP) and GMP grade Raw Materials

Custom GMP-grade Protein Services

Nucleic Acid Removal

resDetect
Residual Detection Kits

AAV Titer Quantitation

Security studies

Security studies

Gene-editing

Viral vectors are a critical part of genetically modifying immune cells to express CAR receptors and maximize cell therapy efficacy.

GENPower Cas Enzymes

AAV Titer Quantitation

Adeno-associated virus (AAV) vectors are responsible for delivering the modified gene payload to its therapy. We offer AAV titration ELISA kits designed to quantitatively evaluate AAV titer to prepare for vector preparation.

Early Pharmacodynamic Assessment

GMP & Premium(Pre-GMP) Grades

High-quality life science tools and solutions designed for use in cell therapy manufacturing that are animal-origin free, sterile, ultra-low endotoxin, and with related regulatory support.

Custom GMP Services

Can’t find the reagents you are looking for in your studies? Contact us and fill out our inquiry form and we can directly synthesize the perfect GMP product for your needs.

Nucleic Acid Removal

Gene-editing

Viral vectors are a critical part of genetically modifying immune cells to express CAR receptors and maximize cell therapy efficacy.

GENPower Cas Enzymes

AAV Titer Quantitation

Large-Scale Manufacturing

Scale-up your current manufacturing with us! We can scale up our GMP-products in accordance to your needs starting from g to kg of GMP-grade products.

Residual Detection

Potency Assay

Potency assays are a critical part of evaluating therapeutic efficacy against the target it was developed for. Use our kits to quickly study your therapeutic potency.

Functional Cell lines (Cellinsight)

Analysis and evaluation at the cellular level is one of the important indicators for evaluating drug effectiveness in vitro and is widely used in the process of new drug development.

AAV Titer Quantitation

Pharmacodynamic Studies

Toxicity Studies

A potential side effect of gene therapies is cytokine release syndrome. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

Security studies

The safety study of preclinical and clinical stages in gene therapy is crucial. Anti-AAV Antibody ELISA Kit can not only provide important reference for screening suitable experimental animals and subjects, optimizing gene therapy plans, but also monitor the safety of gene therapy products, evaluate efficacy, and support product registration and marketing.

Biomarker and Translational Research

Toxicity Studies

A potential side effect of gene therapies is cytokine release syndrome. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

Security studies

FLAG
Transmembrane Proteins

Discovery & Development
CMC-Manufacturing
CMC-Quality Control
Preclinical Studies
Clinical Studies

Immune Checkpoint Proteins

Biotinylated Proteins

ComboX
Fc Proteins

Early Pharmacodynamic Assessment

GENIUS
Nucleic Acid Removal

resDetect
Residual Detection Kits

Enzymes for Antibody Characterization

ComboX
IgG Isotype Control

Therapeutic Antibody Targets

Therapeutic antibodies target a wide variety of tumor biomarkers to target and home onto specific cell types. We offer a wide array of target proteins to assist with the development of antibodies.

Fc Receptor Proteins

The efficacy of a therapeutic antibody depends on the Fc fragment and its interaction with key Fc receptors. Test your antibody against a panel of receptors during antibody engineering.

Antibody Screening Tools

Screening antibody workflows can take on various forms with different reagents and instruments used. Explore our wide array of reagents to assit with developing your own screneing workflow.

Functional Cell lines (Cellinsight)

Analysis and evaluation at the cellular level is one of the important indicators for evaluating drug effectiveness in vitro and is widely used in the process of new drug development.

Early Pharmacodynamic Assessment

Immunohistochemistry (IHC) Antibodies

Nucleic Acid Removal

Enzymes for Antibody Characterization

Undertstanding the conjugation and sequence of antibodies are critical for development success.

Antibody Characterization Services

Several key elements of antibody drug characterization include accurate amino acid sequencing, molecular weight determination, stability, and degree of polymerization. Stability is the main basis for determining the service life of pharmaceutical preparations.

Quality Characterization Analytical Service

Residual Detection

Functional Cell lines (Cellinsight)

Analysis and evaluation at the cellular level is one of the important indicators for evaluating drug effectiveness in vitro and is widely used in the process of new drug development.

Other Quality control Products (Isotype Control)

Setting up corresponding isotype control antibodies to detect non-specific binding can reduce the occurrence of false positive results and accurately assess possible influencing factors during drug development. Explore our isotype control antibodies for your research.

Quality Control Analysis Services

According to pharmacopoeia standards and relevant laws and regulations, the development of antibody drugs need to establish a comprehensive quality control standards, complete the binding activity (drug and target binding and Fc segment and FcR combination) control analysis.

SPR /BLI Analytical Service

CMC Release Method Development Service

Develop CMC release methods to provide the analytical method validation, testing and documentation necessary to support the drug application.

Enzyme-Linked Immunosorbent Assay (ELISA) Service

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models.

Pharmacodynamic Studies

Toxicity Studies

Cytokine release syndrome is a major concern for all new therapeutics. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

Immunogenicity Studies

Evaluating the immunogenicity of any therapeutic is critical in ensuring safety along with other toxicity studies.

Anti-idiotypic Antibody Development Service

Immunohistochemistry (IHC) Antibodies

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models.

Biomarker and Translational Research

Toxicity Studies

Cytokine release syndrome is a major concern for all new therapeutics. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

Immunogenicity Studies

Evaluating the immunogenicity of any therapeutic is critical in ensuring safety along with other toxicity studies.

Anti-idiotypic Antibody Development Service

Immunohistochemistry (IHC) Antibodies

Internalization Mechanism Characterization

Discovery & Development
CMC-Manufacturing
CMC-Quality Control
Preclinical Studies
Clinical Studies

Antibody Screening

Fc Effector Function Validation

Linker Screening and Validation

ADC Conjugation Kits

Internalization Mechanism Characterization

Fc Effector Function Validation

Residual Detection

Enzymes for Antibody Characterization

Antibody Characterization Services

Antibody Screening

In an Ideal ADC, antibody is a crucial vehicle for the specific binding with target antigen. At present, the conventional antibody screening technologies widely used include hybridoma technology, antibody library screening technology, B cell cloning technology and other screening technologies.

Internalization Mechanism Characterization

ADC targets cancer cell antigens through antibodies, delivering cytotoxic drugs directly into tumor cells via internalization, which significantly reduces side effects. The internalization efficiency directly impacts the amount of payload delivered, making it a key evaluation criterion in drug design, including antibody screening and linker optimization.

Antibody Internalization Detection Reagent

Fc Effector Function Validation

The Fc effector function refers to the biological activities triggered by the interaction of the antibody Fc region with Fc receptors (FcRs) on immune cells or the complement system. It is one of the key mechanisms underlying the therapeutic effects of antibody drugs. Fc receptor-mediated effector functions include ADCC, ADCP, and CDC.

Fc Receptor Proteins

Linker Screening and Validation

In the development of ADCs, the linker structure impacts stability, homogeneity, cytotoxic potency, tolerability, and pharmacokinetics (PK). Therefore, selecting the appropriate linker is crucial for optimizing the therapeutic potential and safety of ADCs.

ADC proteases for peptide linker

ADC Conjugation Kits

Conjugating a payload onto antibodies can be challenging with the wide variety of methodologies and linkers. Use our kits to quickly conjugate your target payload onto antibodies in a site-specific methodology.

Internalization Mechanism Characterization

Antibody Internalization Detection Reagent

Fc Effector Function Validation

Fc Receptor Proteins

Residual Detection

Enzymes for Antibody Characterization

The antibody part of ADCs are a major component that contribute to the therapeutic efficacy. Undertstanding the conjugation and sequence of antibodies are critical for development success.

Antibody Characterization Services

Quality Characterization Analytical Service

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models. For cell therapies, PK assays are desigend to evaluate payload delivery concentration.

Pharmacodynamic Studies

Immunogenicity Studies

Evaluating the immunogenicity of any therapeutic is critical in ensuring safety along with other toxicity studies.

Anti-idiotypic Antibody Development Service

Toxicity Studies

Cytokine release syndrome is a major concern for all new therapeutics. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

Immunohistochemistry (IHC) Antibodies

Pharmacokinetic Studies

Pharmacokinetics is a major component of evaluating drug efficacy throughout cell-based or animal models. For cell therapies, PK assays are desigend to evaluate payload delivery concentration.

Biomarker and Translational Research

Toxicity Studies

Cytokine release syndrome is a major concern for all new therapeutics. Ensuring that the therapy is not toxic is a priority to any therapy during the preclinical and clinical stages.

Immunogenicity Studies

Evaluating the immunogenicity of any therapeutic is critical in ensuring safety along with other toxicity studies.

Anti-idiotypic Antibody Development Service

Immunohistochemistry (IHC) Antibodies

resDetect
Residual Detection Kits

Discovery & Development
CMC-Manufacturing
CMC-Quality Control
Preclinical Studies
Clinical Studies

ViruStop
Viral Antigens

ELISpot Assay Kits

GENPower Cas Enzymes

Viral Antigen Detection

Vaccine Efficacy Assessment

Vaccine Efficacy Assessment

ELISpot Assay Kits

Vaccine Efficacy Assessment

ELISpot Assay Kits

Virustop

Virus antigens play a critical role in viral infection. We offer a wide array of antigens for infectious diseases including:

Antigen Detection

Evaluating the presence of antigen is required to ensure that vaccines are delivering the correct virus antigen to induce antibody production.

Vaccine Efficacy Assessment

Vaccine efficacy assessment is important for evaluating the performance of Vaccines. IgG titer and neutralizing antibody titer detection assays are commonly used to predict vaccine efficacy .

Gene-editing

Modification of nucleic acids and other virus vectors are a critical part of vaccine development. Enzymes designed for synthesizing nucleic acids include:

GENPower Cas Enzymes

Antigen Detection

Evaluating the presence of antigen is required to ensure that vaccines are delivering the correct virus antigen to induce antibody production.

Residual Detection

Vaccine Efficacy Assessment

Vaccine efficacy assessment is important for evaluating the performance of Vaccines. IgG titer and neutralizing antibody titer detection assays are commonly used to predict vaccine efficacy .

Toxicity Studies

Ensuring that vaccines delivered are not toxic is a priority to any therapy during the preclinical and clinical stages.

Vaccine Efficacy Assessment

Vaccine efficacy assessment is important for evaluating the performance of Vaccines. IgG titer and neutralizing antibody titer detection assays are commonly used to predict vaccine efficacy .

Toxicity Studies

Ensuring that vaccines delivered are not toxic is a priority to any therapy during the preclinical and clinical stages.