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DLL3 Molecule Information

Name:Delta-like protein 3
Target Synonym:Delta3;Drosophila Delta homolog 3;DLL3
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Phase ?

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Cat. No. Species Product Description Structure Purity Feature
DL3-H52H4 Human Human DLL3 Protein, His Tag
DL3-H5255 Human Human DLL3 Protein, Fc Tag

DLL3 Molecule Synonym Name

Delta3, delta-like 3 (Drosophila), delta-like protein 3, DLL3, Pudgy, SCDO1, SCDO1delta3

DLL3 Molecule Background

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

DLL3 References

DLL3 Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
89Zr-DFO-SC16.56 89Zr-DFO-SC16.56 Phase Ⅰ Memorial Sloan Kettering Cancer Center Small cell lung cancer (SCLC) Details
HPN-328 HPN-328 Phase Ⅱ Harpoon Therapeutics Small cell lung cancer (SCLC) Details
AMG-119 (Amgen) Phase Ⅰ Amgen Small cell lung cancer (SCLC) Details
AMG-757 AMG-757 Phase Ⅰ Amgen Small cell lung cancer (SCLC) Details
Rovalpituzumab tesirine SC16LD6.5; SC-0002; P256HB60FF; SC0001-SCX; SC0001SCX Phase Ⅲ Abbvie, Stemcentrx Small cell lung cancer (SCLC), Solid tumours Details

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