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Your Position: Home > DLL3

DLL3

DLL3 Molecule Information

Name:Delta-like protein 3
Target Synonym:Delta3;Drosophila Delta homolog 3;DLL3

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Phase ?

DLL3 Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description	Structure	Purity	Feature
DL3-H52H4	Human	Human DLL3 Protein, His Tag
DL3-H5255	Human	Human DLL3 Protein, Fc Tag

DLL3 Molecule Synonym Name

Delta3, delta-like 3 (Drosophila), delta-like protein 3, DLL3, Pudgy, SCDO1, SCDO1delta3

DLL3 Molecule Background

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

DLL3 References

DLL3 Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
AMG-119 (Amgen)		Phase Ⅰ	Amgen	Small cell lung cancer (SCLC)	Details
AMG-757	AMG-757	Phase Ⅰ	Amgen	Small cell lung cancer (SCLC)	Details
Rovalpituzumab tesirine	SC16LD6.5; SC-0002; P256HB60FF; SC0001-SCX; SC0001SCX	Phase Ⅲ	Abbvie, Stemcentrx	Small cell lung cancer (SCLC), Solid tumours	Details