Organoid Solutions | Cardiac, Brain & Liver Models

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Overview

Organoids are advanced 3D in vitro cell models that closely mimic the structure, microenvironment and function of human organs, acting as core cutting-edge tools for drug R&D and greatly enhancing the clinical relevance and translation efficiency of research data. We develop standardized, high-stability organoid models with rigorous construction and full-process quality control. Our models boast high structural fidelity, stable performance and excellent batch-to-batch consistency, making them ideal for high-throughput drug screening, efficacy testing and preclinical safety evaluation, and providing reliable in vivo-like experimental support for innovative drug development and clinical translation.

Ready-to-Use
No differentiation or complex induction required. Ready for immediate use upon delivery, cutting culture time and resources.
Highly Biomimetic
Self-assembled 3D tissue with multiple native cell types to mimic physiological microenvironments.
Stable Functional Performance
Captures tissue-specific activities and phenotypic responses for reproducible toxicity testing.
Multidimensional QC
Batch-consistent morphology, markers and function; well-controlled organoid size and structure.

Operating Videos

Organoid Recovery
Organoid Medium Change
Organoid Transfer
Organoid Fixation
Organoid Cryosectioning
Organoid Immunostaining

Organoid Recovery

Organoid Medium Change

Organoid Transfer

Organoid Fixation

Organoid Cryosectioning

Organoid Immunostaining

Product Categories

Ready-to-Use Organoids & Maintenance Kits
Physiologically relevant and functionally validated organoids for drug toxicity assessment.
Cardiac Organoids
Cardiac Organoid Maintenance Kits
Dorsal Forebrain Organoids
Dorsal Forebrain Organoid Maintenance Kits
Organoid Culture Reagents
Essential reagents and consumables for reliable 3D organoid culture and maintenance.
Matrigel Matrix Basement Membrane Extracts
Cytokines for Organoid Culture
Ultra-Low Attachment Plates (6 wells)
Ultra-Low Attachment Plates (96 wells)

Our Services

Drug-Induced Cardiotoxicity Assessment Service
Integrated human iPSC-derived cardiac organoids with MEA technology for reliable, real-time cardiotoxicity assessment in preclinical drug development.
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FAQ

Q
How can organoids reduce the use of animal models in preclinical testing?
Organoids are human-relevant 3D models that can help reduce the use of animal models in preclinical research, supporting the 3R principles. By reproducing key aspects of human tissue structure, cellular interactions, and function, organoids can provide physiologically relevant data for drug efficacy and toxicity assessment while addressing species-specific differences that can limit the translation of findings from animal studies to humans.
Q
How do organoids compare with 2D cell cultures?
Compared with conventional 2D cell models, organoids are 3D in vitro model generated from stem or progenitoe cells that better reproduce spatial organization, cellular interactions, and tissue-specific functions. These features allow organoids to more closely reflect tissue-level responses to drug treatment, providing a more physiologically relevant platform for evaluating drug efficacy and toxicity.
Q
Which organoids are used for drug toxicity testing?
Different organoid models can be used to investigate organ-specific drug toxicity. iPSC-derived cardiac organoids, for example, can support cardiac safety studies through measurements such as beating activity, electrophysiological responses, and calcium dynamics. Dorsal forebrain organoids can be used for neurotoxicity studies, including the evaluation of drug-induced changes in neuronal activity, hyperexcitability, and excitotoxicity.Both types of organoids can be integrated with MEA platforms to assess electrophysiological activity and drug-induced functional changes.
Q
What are ready-to-use organoids?
Ready-to-use organoids are pre-differentiated and functionally characterized 3D models that require only a short recovery period before use，without the need for in-house differentiation from iPSCs. They can significantly shorten model preparation time, reduce hands-on effort, and simplify experimental workflows. With key parameters such as morphology, marker expression, and functional performance assessed before shipment, ready-to-use organoids provide better consistency across experiments and studies.
Q
How are organoids quality-controlled for drug testing?
Organoid quality is assessed across multiple parameters to ensure batch-to-batch consistency and reliable experimental performance. Key criteria include organoid size and morphology, tissue-specific marker expression, and functional characteristics . ACROBiosystems applies comprehensive quality control to each batch and provides a Certificate of Analysis (COA) with clear quality documentation. These measures help support consistent organoid performance in preclinical drug screening and safety studies.

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Overview

Ready-to-Use

Highly Biomimetic

Stable Functional Performance

Multidimensional QC