>SPR /BLI analytical service
Biomolecular interaction analysis is used increasingly in drug development to kinetically characterize binding events of relevant components, including drugs and targets, antibodies and antigens or any pair of interacting molecules including protein-protein, protein-nucleic acid and protein-lipid interactions. Based on the Biacore T200/8K platform and ForteBio Octet platform, ACROBiosystems provides SPR /BLI analytical services to our valued customers. The SPR/BLI analytical services include antibody screening, antibody pairing/group, kinetic analysis, and interaction measurement.
All Fc receptor proteins needed are free of charge
Only provide analytes, then get the full service
Anti- BCMA antibodies (Mouse IgG1) captured on CM5 chip via anti-Mouse IgG antibodies, can bind to Human BCMA Protein, His Tag (Cat. No. BCA-H522y) as determined using a SPR (Biacore T200).
Opdivo (Nivolumab) loaded on Protein A Biosensor, can bind to Human PD-1, His Tag (HPLC-verified) (Cat. No. PD1-H5221) with an affinity constant of 5.09 nM as determined using a BLI assay (ForteBio Octet Red96e).
Human CD64, His Tag (SPR & BLI verified) immobilized on CM5 Chip via an anti-His antibody, can bind to Herceptin with an affinity constant of 5.45 nM as determined in a SPR assay (Biacore T200) (QC tested).
Human CD64, His Tag (SPR & BLI verified) loaded on HIS1K Biosensor, can bind to Herceptin with an affinity constant of 13 nM as determined in a BLI assay (ForteBio Octet Red96e) (Routinely tested).
Trastuzumab can bind to C1q with an affinity constant of 3.24 nM as determined in BLI assay (ForteBio Octet Red96e).
SARS-CoV-2 3CL-Mpro, His Tag immobilized on CM5 Chip can bind to Dipyridamole with an affinity constant of 65.1 μM as determined in a SPR assay (Biacore T200) (Routinely tested).
Using in house protein products, such as Fc receptor proteins, immunological checkpoint proteins, biotin-labeled proteins, etc. can guarantee the assay performance.
We have a professional team with abundant SPR experience to develop and optimize the SPR assays.
You will hear back from our established project management team within one day. We provide frequent and detailed updates and follow-ups to make sure you keep track of your projects.
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