A-Z> Antigens & Antibodies for Diagnostic Kit Development
The current methods of detecting SARS-CoV-2 infection include nucleic acid detections, antibody detections, and antigen detections. Compared to nucleic acid detections, antibody detections and antigen detections are faster and more convenient. Therefore, they are suitable for scenarios such as rapid screening and instant detection.
The sensitivity and specificity of the serological diagnostic kits are significantly affected by the quality of antigen and antibody reagents. To better support the development of the diagnostic kits, ACROBiosystems has developed a serial of high-quality antigen and antibody reagents. Furthermore, several in vitro diagnostics companies are using ACRO's reagents to develop COVID-19 serological diagnostics products. Among them, Babson Diagnostics, a US diagnostics company, successfully obtained the Emergency Use Authority from FDA and launched their chemiluminescent COVID-19 antibody detection kit employing ACRO's biotin-labeled S1 protein.
ACROBiosystems has launched matched antibody pairs specifically designed for diagnostic kits. The sensitivity of the ELISA assays using our matched antibody pairs can reach 12 pg/mL, which is very impressive. What's more, the affinity of these antibodies towards their antigens can be as low as 0.01 nM level. Thus, they are perfect for different antigen detection assays, such as chemiluminescent immunoassay, ELISA, gold immunochromatography assay, etc.
We now offer free samples to the researchers working on the diagnostic kit development. Get it now!
| Category | Cat. No. | Species | Product Description | |
|---|---|---|---|---|
| Nucleocapsid protein Antibody Pair | NUN-S41A1 | Human | Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 (recommended as capture antibody when applied for ELISA) | Inquiry |
| NUN-S42A1 | Human | Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 (recommended as detection antibody when applied for ELISA) | Inquiry | |
| Nucleocapsid protein Antibody Pair | NUN-S46 | Mouse | Anti-SARS-CoV-2 Nucleocapsid Antibody, Mouse mAb (recommended as capture antibody when applied for ELISA) | Inquiry |
| NUN-S47 | Mouse | Anti-SARS-CoV-2 Nucleocapsid Antibody, Mouse mAb (recommended as detection antibody when applied for ELISA) | Inquiry | |
| S1 protein Antibody Pair | S1N-M12A1 | Mouse | Anti-SARS-CoV-2 Spike S1 Antibody, Chimeric mAb (recommended as capture antibody when applied for ELISA) | Inquiry |
| S1N-M13A1 | Mouse | Anti-SARS-CoV-2 Spike S1 Antibody, Chimeric mAb (recommended as detection antibody when applied for ELISA) | Inquiry |
>>> If you have any bulk order inquiry, please feel free to click here.
Fig 1 Immobilized Anti- SARS-CoV-2 Nucleocapsid antibody, mouse Mab (Cat. No. NUN-S46) at 4 μg/mL, add increasing concentrations of SARS-CoV-2 Nucleocapsid protein and then add Biotinylated Anti- SARS-CoV-2 Nucleocapsid antibody, mouse Mab (Cat. No. NUN-S47). Detection was performed using HRP-conjugated streptavidin with sensitivity of 12 pg/mL.
Fig 3 Demonstration of the specificity of Anti-SARS-CoV-2 N antibody (Cat. No. NUN-S42) to the Nucleocapsid protein.
Fig 4 Demonstration of the Batch to Batch Consistency of Anti-SARS-CoV-2 Spike S1 Antibody, Chimeric Mab (Cat. No. S1N-M122) to the S1 protein.
ACROBiosystems has designed Spike and Nucleocapsid antigens specifically for diagnostic kits development. The antigens are customizable and bulk order is available. They are perfect for different antibody detection methods, such as chemiluminescent immunoassay, ELISA, gold immunochromatography assay, etc.
| Molecule | Cat. No. | Species | Product Description | |
|---|---|---|---|---|
| S protein | SPN-C52H2 | HEK293 | SARS-CoV-2 (COVID-19) S protein (R683A, R685A) , His Tag, active trimer (MALS verified) | Inquiry |
| S1 protien | S1N-C52H2 | HEK293 | SARS-CoV-2 (COVID-19) S1 protein, His Tag (MALS verified) | Inquiry |
| S1N-C82E8 | HEK293 | Biotinylated SARS-CoV-2 (COVID-19) S1 protein, His,Avitag™ (MALS verified) | Inquiry | |
| S2 protein | S2N-C52H2 | HEK293 | SARS-CoV-2 (COVID-19) S2 protein, His Tag | Inquiry |
| RBD protein | SPD-C52H1 | HEK293 | SARS-CoV-2 (COVID-19) S protein RBD, His Tag (MALS verified)* | Inquiry |
| SPD-C52H2 | HEK293 | SARS-CoV-2 (COVID-19) S protein RBD, His Tag (MALS verified)* | Inquiry | |
| SPD-C5251 | HEK293 | SARS-CoV-2 (COVID-19) S protein RBD, Mouse IgG2a Fc Tag | Inquiry | |
| SPD-C82E9 | HEK293 | Biotinylated SARS-CoV-2 (COVID-19) S protein RBD, His,Avitag™ (MALS verified) | Inquiry | |
| Nucleocapsid protein | NUN-C5221 | HEK293 | SARS-CoV-2 (COVID-19) Nucleocapsid protein, His Tag | Inquiry |
| NUN-C51H2 | E.coli | SARS-CoV-2 (COVID-19) Nucleocapsid protein, His Tag | Inquiry | |
| NUN-C81Q8 | E.coli | Biotinylated SARS-CoV-2 (COVID-19) Nucleocapsid protein, His,Avitag™ | Inquiry | |
| Envelope Protein | ENN-C5128 | HEK293 | SARS-CoV-2 (COVID-19) Envelope protein, GST,His Tag | Inquiry |
*RBD proteins, SARS-CoV-2 (COVID-19) S protein RBD, His Tag (MALS verified) with Cat.No. SPD-C52H1 and SPD-C52H2 were expressed in different sequence regions.
>>> If you have any bulk order inquiry, please feel free to click here.
>>> If you have any custom inquiries or suggestions for SARS-CoV-2 (COVID-19) related products, please click here.
Fig.5 Immobilized SARS-CoV-2 Nucleocapsid protein, His Tag at 2 μg/mL (100 μL/well) can bind SARS-CoV-2 NP Antibody, Rabbit MAb (CLN27) with a linear range of 0.02-0.3 ng/mL.
>>> All SARS-CoV-2 related products 
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