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SARS-CoV-2 S protein, His Tag, Super stable trimer (MALS verified)

Cat. No. / Size
Price
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SPN-C52H7-200ug
$1,485.00
In Stock - Delivery in 1-2 business days
SPN-C52H7-1mg
$5,080.00
In Stock - Delivery in 1-2 business days
SPN-C52H7-10mg (5mg X 2)
$36,915.00
In Stock - Delivery in 2-3 weeks
SPN-C52H7-100mg
$295,320.00
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SPN-C52H7
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  • Product Details
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Synonyms

Spike, S protein, Spike glycoprotein, S glycoprotein

Source

SARS-CoV-2 S protein, His Tag, Super stable trimer (SPN-C52H7) is expressed from human 293 cells (HEK293).

Predicted N-terminus: Val 16

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 138.0 kDa. The protein migrates as 170-250 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

Formulation

Supplied as 0.2 μm filtered solution in 0.1 M Sodium citrate, pH5.5.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.
ACRO Quality Management System

Background

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.