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Your Position: Home > Viral Proteins > Nucleocapsid protein > NUN-C5221
  • Synonym
    Nucleocapsid protein,NP,Protein N,COVID-19
  • Source
    SARS-CoV-2 Nucleocapsid protein, His Tag (NUN-C5221) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1).
    Predicted N-terminus: Met 1
  • Molecular Characterization
    Online(Met 1 - Ala 419) QHO62115.1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 47.3 kDa.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Formulation

    Delivered as bulk protein in a 0.2 μm filtered solution of 10 mM PB, 150 mM NaCl, pH7.4.

    Contact us for customized product form or formulation.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;

    2. -70°C for 3 months under sterile conditions.

  • Shipping
    This product is supplied as sterile liquid solution and shipped frozen with dry ice, please inquire the shipping cost.
  • Background
    Nucleocapsid protein is a most abundant protein of coronavirus. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. While screening for ADP-ribosylated proteins during coronavirus (CoV) infection, we identified as the viral nucleocapsid (N) protein. Novel post-translation modification of the CoV N protein that may play a regulatory role for this important structural protein. The array of diverse functional activities accommodated in the hantaviral N protein goes far beyond to be a static structural protein and makes it an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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