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Your Position: Home > SARS-CoV-2 Related Kit Products

SARS-CoV-2 Related Kit Products

Background

High-quality recombinant antigen proteins and kit products are critical in accelerating the research and development of anti-SARS-CoV-2 drugs and vaccines.

ACROBiosystems has developed a series of kit products using its high-quality SARS-CoV-2 antigen proteins to improve the efficiency of anti-SARS-CoV-2 drugs and vaccines development. These kit products include SARS-CoV-2 antibody titer serologic assay kits, antigen detection kits, inhibitor screening kits and antigen pre-coated plates and these products can be used for SARS-CoV-2 neutralizing antibody screening, antibody detection and antigen detection.

>>>Accelerated Progress Towards Vaccine Efficacy Evaluation

An increasingly number of people are getting vaccinated to acquire protection against SARS-CoV-2, meanwhile the original wild type virus is evolving to acquire increased fitness that may help evade vaccine-induced immune surveillance. In face of this “Red Queen”1 challenge, how strong the current vaccine protection is against the circulating and emerging variants of the virus becomes a primary concern. Although multiple neutralizing antibody tests have been developed to evaluate vaccine effectiveness against the wild type virus, an important assessment tool to perform this function against the variants is missing.

Now, the gap between what we have and what we need is closed by the successful development of neutralizing antibody titer kits specifically designed for three major SARS-CoV-2 variants, namely B.1.1.7 (the U.K. variant), B.1.351 (South African variant) and P.1 (Brazilian variant). These kits are based on competitive ELISA assays to detect the presence of neutralizing/blocking antibodies in human serum that can specifically inhibit the binding of mutated spike trimer or spike RBD protein to its human receptor ACE2. With verified high sensitivity and specificity, these kits are convenient to use under standard lab condition and can test many samples at the same time. >>Find out more

Popular products
Neutralizing antibody titer assay kit
> Anti-SARS-CoV-2 Neutralizing Antibody Titer Serologic Assay Kit

Correlation analysis of RAS-N022 and FDA approved ELISA kit (detection of neutralizing antibody in post-vaccination serum)

>>> Related article:Neutralizing Antibodies in the Fight against COVID-19

>Anti-SARS-CoV-2 Variants Neutralizing Antibody Titer Serologic Assay Kit
Detection of neutralizing antibody in post-vaccination serum samples

Anti-SARS-COV-2 Neutralizing Antibody Titer Serologic Assay Kit based on WT RBD (Cat.# RAS-N022), B.1.1.7 RBD (Cat.# RAS-N028), B.1.351 RBD (Cat.# RAS-N031), P.1 RBD (Cat.# RAS-N034) are used to detect neutralizing antibodies in 56 post-vaccination serum samples in order to evaluate vaccine efficacy against SARS-CoV-2 Variants of Concerns (VOC).

Detection of inhibiting ability of neutralizing antibodies in blocking SARS-CoV-2 RBD/human ACE2 interaction

Anti-SARS-CoV-2 (B.1.1.7) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) (Cat.No.RAS-N028) is used to detect the inhibition of SARS-CoV-2 RBD/human ACE2 interaction by anti-SARS-CoV-2 neutralizing antibodies Cat. No. S1N-M122, Cat. No. SPD-M128 and Cat. No. SPD-M180. As shown in the figure above, Cat. No. S1N-M122 is more potent than Cat. No. SPD-M128 and Cat. No. SPD-M180 in blocking SARS-CoV-2 RBD/human ACE2 interaction.

Anti-SARS-CoV-2 (B.1.351) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) (Cat.No.RAS-N031) is used to detect the inhibition of SARS-CoV-2 RBD/human ACE2 interaction by anti-SARS-CoV-2 neutralizing antibodies Cat. No. S1N-M122, Cat. No. SPD-M128 and Cat. No. SPD-M180. As shown in the figure above, Cat. No. S1N-M122 is more potent than Cat. No. SPD-M128 and Cat. No. SPD-M180 in blocking SARS-CoV-2 RBD/human ACE2 interaction.

IgG/IgM/total antibody titer assay kit
> Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kit (Spike RBD)
RAS-T024

Detection of Monoclonal Anti-SARS-CoV-2 Antibody, Human IgG1 titer by Indirect-ELISA Assay.Immobilized SARS-CoV-2 Spike RBD at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-SARS-CoV-2 Antibody, Human IgG1 in 1:400 human serum. Detection was performed using HRP-Anti-human IgG antibody with sensitivity of 98 ng/mL.

> Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kit (Spike Trimer)
RAS-T025

Detection of Anti-SARS-CoV-2 Antibody, Human IgG1 titer by Indirect-ELISA Assay.Immobilized SARS-CoV-2 Spike Protein at 2 μg/mL (100 μL/well) can bind monoclonal Anti-SARS-CoV-2 Antibody, Human IgG1 in 1:400 human serum. Detection was performed using HRP-Anti-human IgG antibody with sensitivity of 48 ng/mL.

Antibody isotype assay kit
> Anti-SARS-CoV-2 IgG1/ IgG 2/ IgG 3/ IgG 4 Titer Serologic Assay Kit (S Protein RBD)

Fig.4 cross-validation data for antibody subtype detection

>>> related article:SARS-CoV-2 Infection: Do You Know About the Antibody-Dependent Enhancement (ADE)?

Antigen titer assay kit
> SARS-CoV-2 Spike Protein Titer Assay Kit

Fig.5 This assay kit employs a standard sandwich-ELISA format, providing a rapid detection of SARS-CoV-2 Spike protein. The kit consists of pre-coated Anti-SARS-CoV-2 Spike Protein Antibody Microplate, SARS-CoV-2 Spike protein as Control, biotin-Anti-SARS-CoV-2 Spike protein antibody and HRP-Streptavidin. Detection is performed using HRP-Streptavidin with sensitivity of 200 pg/mL.

> SARS-CoV-2 Spike RBD Titer Assay Kit

Fig.6 Detection mutant and wide type SARS-CoV-2 S protein RBD by ELISA Kit

Product List
  • Antibody titer assay kits

  • Antigen titer assay kits

  • Inhibitor screening kits and more

CategorySpeciesCat.No.Product DescriptionsamplePreorder/Order
Neutralizing antibody titer assay kit
SARS-CoV-2
Wild Type
RAS-N022Anti-SARS-CoV-2 Neutralizing Antibody Titer Serologic Assay KitHuman Serum

Preorder

SARS-CoV-2
Alpha | B.1.1.7
(U.K.)
RAS-N028Anti-SARS-CoV-2 (B.1.1.7) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD)Human Serum

Order

SARS-CoV-2
Beta | B.1.351
(South Africa)
RAS-N031Anti-SARS-CoV-2 (B.1.351) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD)Human Serum

Order

SARS-CoV-2
Gamma | P.1
(Brazil)
RAS-N034Anti-SARS-CoV-2 (P.1) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD)Human Serum

Order

SARS-CoV-2
Delta | B.1.617.2
(India)
RAS-N040Anti-SARS-CoV-2 (B.1.617.2) Neutralizing Antibody Serologic Assay Kit (Spike RBD)Human Serum

Preorder

RAS-N041Anti-SARS-CoV-2 (B.1.617.2) Neutralizing Antibody Serologic Assay Kit (Spike Trimer)Human Serum

Preorder

Antibody titer assay kit
SARS-CoV-2
Wild Type
RAS-T024Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike RBD)Human Serum

Preorder

RAS-T025Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike Trimer)Human Serum

Preorder

RAS-T001Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike S1)Human Serum

Order

RAS-T008Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kit (Nucleocapsid Protein)Human Serum

Order

RAS-T009Anti-SARS-CoV-2 Total Antibody Titer Serologic Assay kit (Spike RBD)Human Serum

Order

RAS-T012Anti-SARS-CoV-2 Antibody IgM Titer Serologic Assay Kit (Spike S1)Human Serum

Order

RAS-T013Anti-SARS-CoV-2 Antibody IgM Titer Serologic Assay Kit (Spike RBD)Human Serum

Order

RAS-T018Mouse Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kitMouse Serum

Order

RAS-T023Mouse Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike Trimer)Mouse Serum

Order

RAS-T019Monkey Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kitMonkey Serum

Order

SARS-CoV-2
Alpha | B.1.1.7
(U.K.)
RAS-T026Anti-SARS-CoV-2 (B.1.1.7) Antibody IgG Titer Serologic Assay Kit (Spike RBD)Human Serum

Order

RAS-T027Anti-SARS-CoV-2 (B.1.1.7) Antibody IgG Titer Serologic Assay Kit (Spike Protein)Human Serum

Order

SARS-CoV-2
Beta | B.1.351
(South Africa)
RAS-T029Anti-SARS-CoV-2 (B.1.351) Antibody IgG Titer Serologic Assay Kit (Spike RBD)Human Serum

Order

RAS-T030Anti-SARS-CoV-2 (B.1.351) Antibody IgG Titer Serologic Assay Kit (Spike Protein)Human Serum

Order

SARS-CoV-2
Gamma | P.1
(Brazil)
RAS-T032Anti-SARS-CoV-2 (P.1) Antibody IgG Titer Serologic Assay Kit (Spike RBD)Human Serum

Order

RAS-T033Anti-SARS-CoV-2 (P.1) Antibody IgG Titer Serologic Assay Kit (Spike Protein)Human Serum

Order

Antibody isotype assay kit
SARS-CoV-2
Wild Type
RAS-T014Anti-SARS-CoV-2 Antibody IgG1 Titer Serologic Assay kitHuman Serum

Order

RAS-T015Anti-SARS-CoV-2 Antibody IgG2 Titer Serologic Assay kitHuman Serum

Order

RAS-T016Anti-SARS-CoV-2 Antibody IgG3 Titer Serologic Assay kitHuman Serum

Order

RAS-T017Anti-SARS-CoV-2 Antibody IgG4 Titer Serologic Assay kitHuman Serum

Order

Cat.No.Product DescriptionsamplePreorder/Order
RAS-A010SARS-CoV-2 Nucleocapsid Protein Titer Assay KitVaccine samples

Order

RAS-A020SARS-CoV-2 Spike Protein Titer Assay KitVaccine samples

Order

RAS-A021SARS-CoV-2 Spike RBD Titer Assay KitVaccine samples

Order

LineageCat.No.Product DescriptionsamplePreorder/Order
SARS-CoV-2
(WT)
EP-105SARS-CoV-2 (COVID-19) Inhibitor screening Kitanti-viral drug

Order

EP-107SARS-CoV-2 (WT) Inhibitor Screening Kit (Spike RBD)anti-viral drug

Preorder

SARS-CoV-2
Alpha | B.1.1.7
(U.K.)
EP-108SARS-CoV-2 (B.1.1.7) Inhibitor Screening Kit (Spike RBD)anti-viral drug

Preorder

SARS-CoV-2
Beta | B.1.351
(South Africa)
EP-109SARS-CoV-2 (B.1.351) Inhibitor Screening Kit (Spike RBD)anti-viral drug

Preorder

SARS-CoV-2
Gamma | P.1
(Brazil)
EP-110SARS-CoV-2 (P.1) Inhibitor Screening Kit (Spike RBD)anti-viral drug

Preorder

SARS-CoV-2
Delta | B.1.617.2
(India)
EP-111SARS-CoV-2 (B.1.617.2) Inhibitor Screening Kit (Spike RBD)anti-viral drug

Preorder


SP-12SARS-CoV-2 Spike S1 protein-Coated Plates, Clear, 96-WellHuman Serum

Order


RP-13SARS-CoV-2 Spike protein RBD-Coated Plates, Clear, 96-WellHuman Serum

Order

>>> If you have any customized inquiries or suggestions for SARS-CoV-2 (COVID-19) related product development, please click here.

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