Fc Receptor Proteins

Authentic Human Cell-Expressed Proteins

ACROBiosystems Fc receptor proteins are exclusively produced in HEK293 cells. The proteins retain their authentic post-translational processing, which often translates into high bioactivity and stability.

High Quality and Binding Activity

The consistency in purity and bioactivity is essential in the successful production of biotinylated proteins. All our proteins are evaluated by a variety of methods throughout the production process to ensure all relevant requirements are met.

• Purity greater than 95% by SDS-PAGE and SEC-HPLC

• Bioactivity validated in functional ELISA and SPR

• Endotoxin less than 1EU/µg by the LAL method.

Fig. 1 The purity of human FcRn (Cat. No. FCM-H5286) was greater than 95% as determined in a HPLC analysis.

Fig. 2 Immobilized Human FcRn / FCGRT & B2M Heterodimer Protein (Cat. No. FCM-H5286) on CM5 Chip, can bind Herceptin with an affinity constant of 0.427 μM as determined in SPR assay (Biacore 8K).

Biotinylated Proteins Available

The use of biotin labeling can make your assay development much easier. We offer a variety of ready-to-use biotinylated Fc receptors. These proteins are produced using our in-house developed labeling techniques, which confers high bioactivity and minimal batch-to-batch variation.

Fig. 3 Immobilized Biotinylated Human FcRn / FCGRT & B2M Heterodimer Protein (Cat.No. FCM-H82W4) on SA chip, can bind Herceptin with an affinity constant of 1.47 μM as determined in a SPR assay (Biacore T200).