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Your Position: Home > Protein > GITR > GIR-M5220

Mouse GITR / TNFRSF18 Protein, His Tag

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This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    AITR,GITR,TNFRSF18,CD357
  • Source
    Mouse GITR, His Tag(GIR-M5220) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - His 153 (Accession # Q8C4K3 ).
    Predicted N-terminus: Ser 22
  • Molecular Characterization
    GITR Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 15.5 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
  • Clinical and Translational Updates

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Price(USD) : $350.00

Price(USD) : $2180.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:7 Details
  • Latest Research Phase:Phase 2 Clinical

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