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PA2-M5145-50ug
$400.00
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PA2-M5145-1mg
$2,800.00
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PA2-M5145
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  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

分子别名（Synonym）

PADI2,PAD-H19,KIAA0994,PAD2,PDI2

表达区间及表达系统（Source）

Mouse PADI2, His Tag (PA2-M5145) is expressed from E. coli cells. It contains AA Met 1 - Pro 673 (Accession # Q08642-1).

蛋白结构（Molecular Characterization）

Online-Res(Met 1 - Pro 673) Q08642-1

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 78.3 kDa.

内毒素（Endotoxin）

制剂（Formulation）

Delivered as bulk protein in a 0.2 μm filtered solution of PBS, pH7.4 with glycerol as protectant.

Contact us for customized product form or formulation.

运输（Shipping）

This product is supplied as sterile liquid solution and shipped frozen with dry ice.

存储（Storage）

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. The product MUST be stored at -70°C or lower upon receipt;
  2. -70°C for 3 months under sterile conditions.

Background

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.