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Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG2 (AS35)

  • Description
    Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG2 (AS35) (Cat. No. SPD-S66) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from human 293 cells (HEK293).
  • Isotype
    Human IgG2/kappa
  • Specificity
    This product is a specific neutralizing antibody against SARS-CoV-2 Spike Protein RBD domain and no cross-reactivity was detected against SARS-CoV Spike protein. The cross-reactivity with other coronaviruses has not been tested yet.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 . Normally trehalose is added as protectant before lyophilization.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG2 (AS35) (Cat. No. SPD-S66) SDS-PAGE gel

Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG2 (AS35) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG2 (AS35)Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG2 (AS35) (Cat. No. SPD-S66) ELISA bioactivity

Immobilized SARS-CoV-2 S protein RBD, His Tag (Cat. No. SPD-C52H1) at 2 μg/mL (200 μL/well) can bind Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG2(Cat. No. SPD-S66) with a linear range of 0.2-1.6ng/mL (QC tested)

  • Background
    It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Order Details

Price(USD) : $380.00

Price(USD) : $2500.00

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