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Your Position: Home > Immune Checkpoint Proteins > Galectin-9 > LG9-H5123

Human Galectin-9 / LGALS9 Protein, His Tag

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  • Synonym
    Galectin-9,LGALS9,Ecalectin
  • Source
    Human Galectin-9 Protein, His Tag (LG9-H5123) is expressed from E.coli cells. It contains AA Ala 2 - Thr 323 (Accession # O00182-2).
    Predicted N-terminus: Met 1
  • Molecular Characterization
    Online-Res(Ala 2 - Thr 323) O00182-2

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 38.5 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;

    2. -70°C for 3 months under sterile conditions after reconstitution.

  • Background
    Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.
  • Clinical and Translational Updates

      

  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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