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LG9-H5123-100ug
$350.00
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LG9-H5123-1mg
$2,100.00
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LG9-H5123
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  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

分子别名（Synonym）

Galectin-9,LGALS9,Ecalectin

表达区间及表达系统（Source）

Human Galectin-9 Protein, His Tag (LG9-H5123) is expressed from E. coli cells. It contains AA Ala 2 - Thr 323 (Accession # O00182-2).

Predicted N-terminus: Met 1

蛋白结构（Molecular Characterization）

Online-Res(Ala 2 - Thr 323) O00182-2

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 38.5 kDa.

内毒素（Endotoxin）

制剂（Formulation）

Please contact us for detailed information.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.

Background

Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.