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Your Position: Home > All Other Proteins > STEAP1 > ST1-H52H3

Human STEAP1 Full Length Protein, His Tag (HEK293)

  • Synonym
    STEAP1, PRSS24, STEAP
  • Source
    Human STEAP1 Full Length, His Tag (HEK293) (ST1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 2 - Leu 339 (Accession # Q9UHE8-1).
    Predicted N-terminus: Met
  • Molecular Characterization
    Online(Gln 2 - Leu 339) Q9UHE8-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 41.7 kDa. The protein migrates as 31 kDa and 35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • Shipping
    This product is supplied and shipped as sterile liquid solution with dry ice, please inquire the shipping cost.
SDS-PAGE
Human STEAP1 Full Length, His Tag (HEK293) (Cat. No. ST1-H52H3) SDS-PAGE gel

Human STEAP1 Full Length, His Tag (HEK293) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

  • Background
    Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:2 Details
  • Latest Research Phase:Phase 2 Clinical

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