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Your Position: Home > Cytokines > FGF-4 > FG4-H52H3

Human FGF-4 Protein, His Tag

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  • Synonym
    FGF-4, Fibroblast growth factor 4, HST, HST-1
  • Source
    Human FGF-4, His Tag (FG4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 31 - Leu 206 (Accession # P08620-1).
    Predicted N-terminus: Ala 31
  • Molecular Characterization
    Online-Res(Ala 31 - Leu 206) P08620-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 21.2 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Fibroblast growth factor-4 (FGF4) is expressed in embryonic stages and in adult tissues, where it plays critical roles in modulating multiple cellular functions. Fibroblast growth factor 4 (FGF4) is a multipotent growth factor and is highly expressed in various human cancers. In lung adenocarcinoma (ADC) cell lines, FGF4 could alter cell morphology, promote epithelial-mesenchymal transition-associated protein expression, and enhance cell proliferation, migration/invasion and colony initiation. In B-cell lymphoma, FGF4 secretion by cancer cells induces Jag1 expression in neighbor Endothelial cell that in turn activates Notch2 in lymphoma cells.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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