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Your Position: Home > Cytokines > FGF-3 > FG3-H5247

Human FGF-3 / HBGF-3 Protein, His Tag

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  • Synonym
    FGF-3,HBGF-3,Fibroblast growth factor 3
  • Source
    Human FGF-3, His Tag (FG3-H5247) is expressed from human 293 cells (HEK293). It contains AA Ala 18 - His 239 (Accession # P11487-1).
    Predicted N-terminus: His
  • Molecular Characterization
    Online-Res(Ala 18 - His 239) P11487-1

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 26.8 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Fibroblast growth factor 3 (FGF3), belonging to the family of fibroblast growth factors (FGFs), regulates several developmental processes, including brain patterning, branching morphogenesis and limb development, by binding, dimerizing and activating cell surface FGF receptors (FGFRs). FGF/FGFR complexes have been demonstrated to act as driving oncogenes in certain types of cancer to maintain the malignant properties of tumor cells in a cell autonomous manner. According to previous studies, it is speculated that FGF3 is upregulated in breast cancer and accelerates tumor growth and angiogenesis. Consequently, FGF3 has been considered as a potential target for breast cancer therapy.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

Price(USD) : $2310.00

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