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Ad 5,Pre-histone-like nucleoprotein,pVII,Histone-like nucleoprotein,Core protein VII
Human Adenovirus protein VII, Tag Free (AND-H5114) is expressed from undefined It contains AA Ser 2 - Asn 198 (Accession # P68951).
Predicted N-terminus: Met
Request for sequence

This protein carries a polyhistidine tag at the C-terminus
The protein has a calculated MW of 23.9 kDa. The protein migrates as 30-33 kDa under reducing (R) condition (SDS-PAGE).
Less than 0.1 EU per μg by the LAL method.
>95% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in PBS, 0.5 M Arginine, pH7.3 with trehalose as protectant.
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Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
Adenovirus protein VII (pVII) plays a role in the inhibition of host immune response within the nucleus. Interacts with cellular nucleosomes and immobilizes the host immune danger signal HMGB1 on chromatin. In turn, prevents HMGB1 release out of the cell and thus decreases inflammation. Plays also a role in the wrapping and condensation of the viral DNA. May also promote viral genome import into the nucleus.