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This product is in development. If you are interested in this product, please contact us directly. We will accelerate our R&D process according to your needs and reserve the product for you.
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CC3-H52H3-1mg
$3,000.00
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CC3-H52H3-50ug
$360.00
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CC3-H52H3-20ug
$180.00
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CC3-H52H3
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  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

分子别名（Synonym）

C-C motif chemokine 3,MIP1-(a),AI323804,CCL3,chemokine (C-C motif) ligand 3,G0S19-1,LD78a,LD78alpha,MIP1 alpha,MIP-1 alpha,MIP1A,MIP-1alpha,MIP1-alpha

表达区间及表达系统（Source）

Human CCL3, His Tag (CC3-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Ala 92 (Accession # P10147-1).

Predicted N-terminus: Ser 24

蛋白结构（Molecular Characterization）

Online-Res(Ser 24 - Ala 92) P10147-1

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 9.6 kDa.

内毒素（Endotoxin）

制剂（Formulation）

Please contact us for detailed information.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.

Background

CCL3, also know as MIP-1-alpha, is monokine with inflammatory and chemokinetic properties. CCL3 is an important chemokine implicated in both immune surveillance and tolerance, has emerged as a prognostic biomarker in both solid and hematological malignancies. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).