>IL-2 R beta & IL-2 R alpha & IL-2 R gamma
Cynomolgus IL-2RB&IL-2RA&IL-2RG, His Tag&Twin-Strep Tag is produced by co-expression of IL-2RB and IL-2RA and IL-2RG, has a calculated MW of 30.1 kDa (IL-2RB) and 55.9 kDa (IL-2RA&IL-2RG). Subunit IL-2RB is fused with a his tag at the C-terminus and subunit IL-2RA&IL-2RG is fused with a Twin-Strep Tag at the C-terminus. The reducing (R) protein migrates as 37-44 kDa and 85-100 kDa respectively due to glycosylation.
>95% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
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Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, His Tag&Twin-Strep Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, His Tag&Twin-Strep Tag (Cat. No. ILG-C52W3) is more than 85% and the molecular weight of this protein is around 120-140 kDa verified by SEC-MALS.
Immobilized Cynomolgus IL-2, His Tag (Cat. No. IL2-C5249) at 5 μg/mL (100 μL/well) can bind Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, His Tag&Twin-Strep Tag (Cat. No. ILG-C52W3) with a linear range of 2-78 ng/mL (QC tested).
Immobilized Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, His Tag&Twin-Strep Tag (Cat. No. ILG-C52W3) at 5 μg/mL (100 μL/well) can bind Human IL-2 Protein, Fc Tag (Cat. No. IL2-H5269) with a linear range of 0.2-2 ng/mL (Routinely tested).
Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, His Tag&Twin-Strep Tag (Cat. No. ILG-C52W3) captured on CM5 chip via anti-His antibody can bind Human IL-2, Tag Free with an affinity constant of 29.8 pM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Loaded Human IL-2 Protein, Fc Tag (Cat. No. IL2-H5269) on Protein A Biosensor, can bind Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, His Tag&Twin-Strep Tag (Cat. No. ILG-C52W3) with an affinity constant of 0.907 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.
Price(USD) : $350.00
Price(USD) : $2310.00
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