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CD47

CD47 Molecule Information

Name:Cluster of Differentiation 47
Target Synonym:Protein MER6?Integrin-associated protein?Antigenic surface determinant protein OA3?Leukocyte surface antigen CD47?CD47?MER6?CD_antigen: CD47
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:14
Lastest Research Phase:Phase ?

CD47 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
CD7-C52H5 Canine Canine CD47 Protein, His Tag
CD7-C52H5-structure
CD7-C52H5-sds
CD7-C52H5-elisa_1
EP-102 Human CD47: SIRP alpha [Biotinylated] Inhibitor Screening ELISA Assay Pair
EP-102-elisa_1
CD7-H522a Human Human CD47 Protein, low endotoxin
CD7-H522a-structure
CD7-H522a-sds
CD7-H522a-elisa_1
CD7-H5251 Human Human CD47 Protein, Llama IgG2b Fc Tag, low endotoxin
CD7-H5251-structure
CD7-H5251-sds
CD7-H5251-elisa_1
CD7-M525a Mouse Mouse CD47 Protein, Mouse IgG2a Fc Tag, low endotoxin
CD7-M525a-structure
CD7-M525a-sds
CD7-M525a-elisa_1
CD7-M522b Mouse Mouse CD47 Protein
CD7-M522b-structure
CD7-M522b-sds
CD7-M522b-elisa_1
CD7-C52H1 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque CD47 Protein, His Tag
CD7-C52H1-structure
CD7-C52H1-sds
CD7-C52H1-elisa_1
CD7-C52H1-elisa_2
CD7-HA2E9 Human Unconjugated Human CD47 Protein, His Tag, Avi Tag (Avitag™)
CD7-HA2E9-structure
CD7-HA2E9-sds
CD7-HA2E9-elisa_1
CD7-H82E9 Human Biotinylated Human CD47 Protein, Avi Tag (Avitag™)
CD7-H82E9-structure
CD7-H82E9-sds
CD7-H82E9-elisa_1
CD7-R5257 Rabbit Rabbit CD47 Protein, Fc Tag
CD7-R5257-structure
CD7-R5257-sds
CD7-R5256 Rat Rat CD47 Protein, Fc Tag
CD7-R5256-structure
CD7-R5256-sds
CD7-R5256-elisa_1
CD7-H52A5 Human Human CD47 Protein, mouse IgG2a Fc Tag, low endotoxin
CD7-H52A5-structure
CD7-H52A5-sds
CD7-H52A5-elisa_1
CD7-C5252 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque CD47 Protein, Fc Tag
CD7-C5252-structure
CD7-C5252-sds
CD7-C5252-elisa_1
CD7-M5251 Mouse Mouse CD47 Protein, Fc Tag
CD7-M5251-structure
CD7-M5251-sds
CD7-H82F6 Human Biotinylated Human CD47, Fc Tag, Avi Tag (Avitag™)
CD7-H82F6-structure
CD7-H82F6-sds
CD7-H82F6-elisa_1
CD7-H5227 Human Human CD47 Protein, His Tag
CD7-H5227-structure
CD7-H5227-sds
CD7-H5227-elisa_1
CD7-H5227-elisa_2
CD7-H5256 Human Human CD47 Protein, Fc Tag (HPLC-verified)
CD7-H5256-structure
CD7-H5256-sds
CD7-H5256-hplc
CD7-H5256-elisa_1

CD47 Molecule Synonym Name

CD47,MER6,IAP,OA3

CD47 Molecule Background

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

CD47 References

CD47 Related Molecule

CD47 Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
SHR-1603 SHR-1603,SHR1603; SHR 1603 Phase Ⅰ Jiangsu Hengrui Medicine Solid tumours, Lymphoma, Malignancies Details
TTI-622 TTI-622 Phase Ⅰ Trillium Therapeutics Inc Multiple myeloma (MM), Lymphoma Details
ALX-148 ALX-148; ALX148 Phase Ⅰ Alexo Therapeutics Solid tumours, Non-Hodgkin's lymphoma (NHL) Details
IMM01 IMM01,IMM-01 IND Filing ImmuneOnco Cancer Details
Anti-CD47 monoclonal antibody (Biocad) Phase Ⅰ Biocad Cancer Details
CC-90002 CC-90002; INBRX-103 Phase Ⅰ Inhibrx, Celgene Myelodysplastic syndrome (MDS), Acute myeloid Leukemia (AML) Details
TTI-621 TTI-621 Phase Ⅰ The Hospital for Sick Children, University Health Network, Trillium Therapeutics Inc hematological malignancies, Solid tumours, Mycosis fungoides Details
SRF-231 SRF-231 Phase Ⅰ Surface Oncology hematological malignancies, Solid tumours Details
CC-90002-ST-001 CC-90002-ST-001 Phase Ⅰ Cancer Centre of Monoclonal Therapy Breast cancer Details
OSE-172 OSE-172 Preclinical OSE Immunotherapeutics, Boehringer Ingelheim Cancer Details
IBI-188 IBI-188 Phase Ⅰ Innovent Biologics Cancer Details
AO-176 AO-176; Ti-104; Ti-108; Ti-176 Phase Ⅰ Arch Oncology Solid tumours Details
Hu5F9-G4 Hu5F9-G4 Phase Ⅱ Stanford University, Forty Seven Solid tumours, Acute myeloid Leukemia (AML) Details
TG-1801 TG-1801,NI-1701,TG-1801; NI-1701 Phase Ⅰ NovImmune, TG Therapeutics B-cell lymphoma Details

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