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Your Position: Home > CD48

CD48

CD48 Molecule Information

Name:Cluster of Differentiation 48
Target Synonym:CD48;HCD48;SLAMF2;SLAM family member 2;Signaling lymphocytic activation molecule 2;TCT.1;Leukocyte antigen MEM-102;BCM1;B-lymphocyte activation marker BLAST-1;MEM-102;BCM1 surface antigen;BLAST1;MCD48

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase ?

CD48 Part of Bioactivity data

BC1-H5255-ELISA

Immobilized Human 2B4, His Tag (Cat. No. 2B4-H5224) at 2 μg/mL (100 μL/well) can bind Human CD48, Fc Tag (Cat. No. BC1-H5255) with a linear range of 0.078-2.5 μg/mL (QC tested).

Protocol

BC1-H5258-ELISA

Immobilized Human 2B4, Fc Tag (Cat. No. 2B4-H5255) at 2 μg/mL (100 μL/well) can bind Human CD48, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. BC1-H5258) with a linear range of 2-31 ng/mL (QC tested).

Protocol

CD48 Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description
BC1-H5258	Human	Human CD48 / SLAMF2 Protein, Mouse IgG2a Fc Tag, low endotoxin
BC1-H5255	Human	Human CD48 / SLAMF2 Protein, Fc Tag
BC1-H5226	Human	Human CD48 / SLAMF2 Protein, His Tag

CD48 Molecule Synonym Name

CD48,BCM1,SLAMF2,BLAST1,BLAST,BLAST1,MEM-102,TCT.1,BCM-1,SLAMF-2,BLAST-1

CD48 Molecule Background

CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.

CD48 References

CD48 Related Molecule

2B4

CD48 Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
Anti-CD48 monoclonal antibody WM-63		Phase Ⅰ	Nonindustrial source	Chronic lymphocytic leukemia (CLL)	Details
SGN-CD48A	SGN-CD48A	Phase Ⅰ	Seattle Genetics	Multiple myeloma (MM)	Details