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Your Position: Home > CD48

CD48

Brief Information

Name:Cluster of differentiation 48
Target Synonym:Signaling lymphocytic activation molecule 2,BCM1 surface antigen,CD48,BCM1,CD48 Molecule,CD48 Antigen (B-Cell Membrane Protein),B-Lymphocyte Activation Marker BLAST-1,SLAM Family Member 2,CD48 Antigen,BLAST1,SLAMF2,TCT.1,MEM-102,BLAST,HCD48,MCD48,Leukocyt
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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Part of Bioactivity data

BC1-H5255-ELISA
Human CD48, Fc TagHuman CD48, Fc Tag (Cat. No. BC1-H5255) ELISA bioactivity

Immobilized Human 2B4, His Tag (Cat. No. 2B4-H5224) at 2 μg/mL (100 μL/well) can bind Human CD48, Fc Tag (Cat. No. BC1-H5255) with a linear range of 0.078-2.5 μg/mL (QC tested).

BC1-H5258-ELISA
Human CD48, Mouse IgG2a Fc Tag, low endotoxinHuman CD48, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. BC1-H5258) ELISA bioactivity

Immobilized Human 2B4, Fc Tag (Cat. No. 2B4-H5255) at 2 μg/mL (100 μL/well) can bind Human CD48, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. BC1-H5258) with a linear range of 2-31 ng/mL (QC tested).

Synonym Name

CD48,BCM1,SLAMF2,BLAST,BLAST1,MEM-102,TCT.1,BCM-1,SLAMF-2,BLAST-1

Background

CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.

Clinical and Translational Updates

Related Molecule

2B4

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
SGN-CD48A SGN-CD48A Phase 1 Clinical Seattle Genetics Multiple Myeloma Details

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