CD48

CD48 Molecule Information

Name：Cluster of Differentiation 48
Target Synonym：CD48?HCD48?SLAMF2?SLAM family member 2?Signaling lymphocytic activation molecule 2?TCT.1?Leukocyte antigen MEM-102?BCM1?B-lymphocyte activation marker BLAST-1?MEM-102?BCM1 surface antigen?BLAST1?MCD48

Number of Launched Drugs：0
Number of Drugs in Clinical Trials：2
Lastest Research Phase：Phase ?

CD48 Protein Product ListCompare or Buy

Cat. No.	Species	Product Description
BC1-H5258	Human	Human CD48 / SLAMF2 Protein, Mouse IgG2a Fc Tag, low endotoxin
BC1-H5255	Human	Human CD48 / SLAMF2 Protein, Fc Tag
BC1-H5226	Human	Human CD48 / SLAMF2 Protein

CD48 Molecule Synonym Name

CD48,BCM1,SLAMF2,BLAST1,BLAST,BLAST1,MEM-102,TCT.1,BCM-1,SLAMF-2,BLAST-1

CD48 Molecule Background

CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.

CD48 References

CD48 Related Molecule

2B4

CD48 Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
Anti-CD48 monoclonal antibody WM-63		Phase Ⅰ	Nonindustrial source	Chronic lymphocytic leukemia (CLL)	Details
SGN-CD48A	SGN-CD48A	Phase Ⅰ	Seattle Genetics	Multiple myeloma (MM)	Details