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Your Position: Home > PTK7

PTK7

Brief Information

Name:Protein-tyrosine kinase 7
Target Synonym:Colon carcinoma kinase 4,Inactive tyrosine-protein kinase 7,Tyrosine-protein kinase-like 7,CCK-4,PTK7,Protein Tyrosine Kinase 7 (Inactive),Pseudo Tyrosine Kinase Receptor 7,PTK7 Protein Tyrosine Kinase 7,CCK4,Protein-Tyrosine Kinase 7,Protein Tyrosine Kinase 7
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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Cat. No. Species Product Description Structure Purity Feature
PT7-R52H6 Rat Rat PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-R52H6-structure
PT7-R52H6-sds
PT7-R5255 Rat Rat PTK7 / CCK4 Protein, Fc Tag
PT7-R5255-structure
PT7-R5255-sds
PT7-C52H3 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-C52H3-structure
PT7-C52H3-sds
PT7-R52H4 Rabbit Rabbit PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-R52H4-structure
PT7-R52H4-sds
PT7-M52H3 Mouse Mouse PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-M52H3-structure
PT7-M52H3-sds
PT7-H5253 Human Human PTK7 / CCK4 Protein, Fc Tag (MALS verified)
PT7-H5253-structure
PT7-H5253-sds
PT7-H82E5 Human Biotinylated Human PTK7 / CCK4 protein, His,Avitag™ (MALS verified)
PT7-H82E5-structure
PT7-H82E5-sds
PT7-H52H3 Human Human PTK7 / CCK4 Protein, His Tag (MALS verified)
PT7-H52H3-structure
PT7-H52H3-sds
ACRO Quality

Part of Bioactivity data

PT7-R52H6-MALS-HPLC
Rat PTK7, His Tag (Cat. No. ) MALS images

The purity of Rat PTK7, His Tag (Cat. No. PT7-R52H6) is more than 90% and the molecular weight of this protein is around 85-115 kDa verified by SEC-MALS.

Report
  • Background
    PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
  • Clinical and Translational Updates
      

  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

    PT7-C52H3-MALS-HPLC
    Cynomolgus / Rhesus macaque PTK7, His Tag (Cat. No. ) MALS images

    The purity of Cynomolgus / Rhesus macaque PTK7, His Tag (Cat. No. PT7-C52H3) is more than 85% and the molecular weight of this protein is around 80-116 kDa verified by SEC-MALS.

    Report

Customer Reviews

Synonym Name

PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7

Background

PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Cofetuzumab Pelidotin PF-06647020; PF-6647020; PTK7-ADC; PF-06523435; PF-7020; hu-24; ABBV-647; Anti-PTK7 ADC; h6M24-vc0101 Phase 1 Clinical Stemcentrx Inc, Abbvie Inc Neoplasms; Carcinoma, Non-Small-Cell Lung Details

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