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Jagged 1

Jagged 1 Overview

English NameProtein jagged-1Approved Drugs0
Drugs in Clinical Trials2Target SynonymAHD，AWS，AGS，Jagged-1 Protein，Jagged1，Protein jagged-1，JAG1，Jagged 1，JAGL1，Alagille Syndrome，CD339，AGS1，DCHE，Jagged Canonical Notch Ligand 1，hJ1，CD339 Antigen
Highest Development StagePhase 1 Clinical
English NameProtein jagged-1
Target SynonymAHD，AWS，AGS，Jagged-1 Protein，Jagged1，Protein jagged-1，JAG1，Jagged 1，JAGL1，Alagille Syndrome，CD339，AGS1，DCHE，Jagged Canonical Notch Ligand 1，hJ1，CD339 Antigen
Approved Drugs0
Drugs in Clinical Trials2
Highest Development StagePhase 1 Clinical

Jagged 1 Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    His Tag (1)

  • Conjugate

    Unconjugated (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
JA1-H52H9
Human
HEK293
Human Jagged 1 / JAG1 Protein, His Tag
Total: 1
  • 1

Jagged 1 Background

Protein jagged-1 (JAG1) is also known as Jagged1, hJ1, JAGL1 and CD339, which is a single-pass type I membrane protein containing one DSL domain and 15 EGF-like domains. JAG1 is widely expressed in adult and fetal tissues,the expression of JAG1 is up-regulated in cervical squamous cell carcinoma and also expressed in bone marrow cell line HS-27a.JAG1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. JAG1 is involved in early and late stages of mammalian cardiovascular development. JAG1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).

Jagged 1 Synonyms

CD339,JAG1,Jagged1,hJ1,JAGL1

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
AMG-430AMG-430Phase 1 ClinicalAmgen IncCystic Fibrosis; Pulmonary Disease, Chronic Obstructive
Details
ART-104 (Arnatar Therapeutics)ART-104; ART104ClinicalSuzhou Arnatar Therapeutics Co LtdAlagille Syndrome
Details

Product Reviews

  • V***s2021-08-25
    1People Like
    Human Jagged 1 / JAG1 Protein, His Tag
    We are a company in the filed of Antibody Discovery and engineering.. Jagged 1/JAG1 His tag shelps us greatly in searching and characterization of specific antibodies,and detectors. It is a great quality product, and its efficacy is always reliable. It also comes with a certification of analysis, which has very insighful information. We use Acrobiosystems products, because they are easy to order, reliable and fast delivery. Thank you! Victor G.
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