ROR2 Protein - ACROBiosystems

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ROR2

Brief Information

Name:Tyrosine-protein kinase transmembrane receptor ROR2
Target Synonym:EC:2.7.10.1,ROR2,NTRKR2,Receptor Tyrosine Kinase Like Orphan Receptor 2,Tyrosine-Protein Kinase Transmembrane Receptor ROR2,Neurotrophic Tyrosine Kinase, Receptor-Related 2,Neurotrophic Tyrosine Kinase Receptor-Related 2,Receptor Tyrosine Kinase-Like Orph

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical


RO2-H82E3	Human	Biotinylated Human ROR2 / NTRKR2 Protein, His,Avitag™
RO2-M5253	Mouse	Mouse ROR2 / NTRKR2 Protein, Fc Tag
RO2-H52E5	Human	Human ROR2 / NTRKR2 Protein, His Tag
RO2-H5251	Human	Human ROR2 / NTRKR2 Protein, Fc Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

RO2-H82E3

Human

Biotinylated Human ROR2 / NTRKR2 Protein, His,Avitag™

RO2-M5253

Mouse

Mouse ROR2 / NTRKR2 Protein, Fc Tag

RO2-H52E5

Human

Human ROR2 / NTRKR2 Protein, His Tag

RO2-H5251

Human

Human ROR2 / NTRKR2 Protein, Fc Tag

Part of Bioactivity data

RO2-H52E5-ELISA

Immobilized Human ROR2, His Tag (Cat. No. RO2-H52E5) at 1 μg/mL (100 μL/well) can bind Anti-ROR2 Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

Protocol

RO2-H82E3-ELISA

Immobilized Biotinylated Human ROR2, His,Avitag (Cat. No. RO2-H82E3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-ROR2 Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

Protocol

Synonym Name

ROR2,NTRKR2

Background

Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.

Clinical and Translational Updates

Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
BA-3021	BA-3021; CAB-ADC; CAB-ROR2; CAB-ROR2-ADC	Phase 2 Clinical	Bioatla	Triple Negative Breast Neoplasms; Sarcoma; Carcinoma, Non-Small-Cell Lung	Details