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TIM-1

Brief Information

Name:T-cell immunoglobulin mucin receptor 1
Target Synonym:CD365 Antigen,TIMD1,T-cell immunoglobulin mucin receptor 1,TIMD-1,TIM-1,CD365,TIM1,HAVCR1,Hepatitis A Virus Cellular Receptor 1,Kidney Injury Molecule 1,T-Cell Immunoglobulin Mucin Family Member 1,T-Cell Membrane Protein 1,KIM-1,KIM1,TIM,T Cell Immunoglob
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
KI1-H52H3 Human Human TIM-1 / HAVCR1 Protein, His Tag (MALS verified)
KI1-H52H3-structure
KI1-H52H3-sds

Part of Bioactivity data

The purity of (Cat. No. KI1-H5257) was more than 90% and the molecular weight of this protein is around 55-70 kDa verified by SEC-MALS.

  • Background
    Hepatitis A virus cellular receptor 1 is also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Synonym Name

HAVCR1,KIM1,TIM1,TIMD1

Background

Hepatitis A virus cellular receptor 1 is also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.

Clinical and Translational Updates

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