Acrobiosystems for English
icon_bulk_orderBulk inquiry/Quick order
user
  1. Dashboard
  2. My Profile
  3. My Address
  4. My Orders
  5. Acro Membership
Login Register
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |Streptavidin（SA） Hot |Claudin 18.2 |Cadherin-17 
0
There is no goods in the shopping cart !
My Cart|Check Out
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > TGF-beta 3

TGF-beta 3

Brief Information

Name:Transforming growth factor beta 3
Target Synonym:Transforming Growth Factor beta3,TGFB3,LAP,Prepro-Transforming Growth Factor Beta-3,TGF-Beta3,Transforming Growth Factor, Beta 3,ARVD1,LDS5,Arrhythmogenic Right Ventricular Dysplasia 1,RNHF,Transforming growth factor beta-3 proprotein,ARVD
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 2 Clinical

Product ListCompare or Buy

Product> Filter Results
By Product Status:
By Product Category:
By Species:
By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
TG3-H52H5 Human Human Latent TGF-beta 3 / Latent TGFB3 Protein, His Tag
TG3-H52H5-structure
TG3-H52H5-sds
TG3-H82E6 Human Biotinylated Human Latent TGF-beta 3 / Latent TGFB3 Protein, His,Avitag™
TG3-H82E6-structure
TG3-H82E6-sds
TG3-H5213 Human Human TGF-beta 3 / TGFB3 Protein, premium grade
TG3-H5213-structure
TG3-H5213-sds
ACRO Quality

Part of Bioactivity data

TG3-H82E6-ELISA
TGF-beta 3 ELISA

Immobilized Human TGFBR2, Fc Tag (Cat. No. TG2-H5252) at 5 μg/mL (100 μL/well) can bind Biotinylated Human Latent TGFB3, His,Avitag (Cat. No. TG3-H82E6) with a linear range of 0.3-20 ng/mL (QC tested).

Protocol
TG3-H52H5-ELISA
Human Latent TGF-beta 3, His TagHuman Latent TGF-beta 3, His Tag (Cat. No. TG3-H52H5) ELISA bioactivity

Immobilized Human Latent TGF-beta 3, His Tag (Cat. No. TG3-H52H5) at 2 μg/mL (100 μL/well) can bind Biotinylated Human TGFBR2, Fc,Avitag (Cat. No. TG2-H82F6) with a linear range of 0.2-2 ng/mL (QC tested).

Protocol

Synonym Name

TGFB3,ARVD,TGF-beta3

Background

Transforming growth factor beta 3 ( TGFB3) is also known as TGF-β3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development.  TGF-beta 3 is similar with TGF-beta 1 and ­-beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial­-mesenchymal transition.  TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
AVID-200 AVID-200; BMS-986416; AVID-200 DP Phase 1 Clinical Formation Biologics Corp Solid tumours; Neoplasms; Primary Myelofibrosis; Scleroderma, Diffuse Details
Dalutrafusp alfa AGEN-1423; GS-1423 Phase 2 Clinical Gilead Inc, Agenus Inc Solid tumours; Pancreatic Neoplasms; Neoplasms; Carcinoma, Pancreatic Ductal Details

This web search service is supported by Google Inc.

totop
Call us
Call us
North America:
+1 800-810-0816 (Toll Free)
Asia & Pacific:
+86 400-682-2521
Email
Email
order@acrobiosystems.com
Fax
Fax
+1 888-377-6111
Address
Address
1 Innovation Way, Newark, DE 19711, USA
linkedin twitter facebook youtube

Leave a message

Copyright © 2017 ACROBiosystems. All Rights Reserved
|Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap