ALCAM Protein - ACROBiosystems

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ALCAM

Brief Information

Name:Activated leukocyte cell adhesion molecule
Target Synonym:CD166 antigen,Activated leukocyte cell adhesion molecule,CD166,ALCAM,MEMD,Activated Leucocyte Cell Adhesion Molecule,Activated-Leukocyte Cell Adhesion Molecule

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical


CD6-H5259	Human	Human ALCAM Protein, Fc Tag
CD6-H5228	Human	Human ALCAM Protein, His Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

CD6-H5259

Human

Human ALCAM Protein, Fc Tag

CD6-H5228

Human

Human ALCAM Protein, His Tag

Synonym Name

CD166,ALCAM,CD6L,KG-CAM,MEMD

Background

CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins, which is also known as Activated leukocyte cell adhesion molecule (ALCAM) in human, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. CD166 is a cell adhesion molecule that binds to CD6. CD166 involved in neurite extension by neurons via heterophilic and homophilic interactions.

Clinical and Translational Updates

Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
CD166 probody drug conjugate (CytomX Therapeutics/ImmunoGen)	CX-2009	Phase 2 Clinical	Immunogen Inc, Cytomx Therapeutics	Ovarian Neoplasms; Head and Neck Neoplasms; Biliary Tract Neoplasms; Solid tumours; Triple Negative Breast Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung	Details